2-Methyl-3-trifluoromethylaniline

Synonym(s):2-Amino-6-(trifluoromethyl)toluene;2-Methyl-3-(trifluoromethyl)aniline;Flunixin Meglumine Impurity B (Ph. Eur.)

CAS NO.：54396-44-0
Empirical Formula: C8H8F3N
Molecular Weight: 175.15
MDL number: MFCD00153216
EINECS: 259-145-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-21 22:41:43

2-Methyl-3-trifluoromethylaniline Structural

What is 2-Methyl-3-trifluoromethylaniline ?

Chemical properties

White crystalline powder

The Uses of 2-Methyl-3-trifluoromethylaniline

2-Methyl-3-trifluoromethylaniline is a reactant in the synthesis of methylguanidine derivatives as prospective PET radioligands for the open channel of the NMDA receptor, linked to Alzheimer’s, epilepsy and other neurodegenerative disorders.

What are the applications of Application

2-Methyl-3-(trifluoromethyl)aniline is used in chemical synthesis

General Description

2-Methyl-3-(trifluoromethyl)aniline belongs to the trifluoromethylbenzene series.

Properties of 2-Methyl-3-trifluoromethylaniline

Melting point:	38-42 °C(lit.)
Boiling point:	62-64°C 4mm
Density	1.237±0.06 g/cm3(Predicted)
Flash point:	>210 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka	3.23±0.10(Predicted)
form	Crystalline Powder
color	White
BRN	2832865
InChI	InChI=1S/C8H8F3N/c1-5-6(8(9,10)11)3-2-4-7(5)12/h2-4H,12H2,1H3
CAS DataBase Reference	54396-44-0(CAS DataBase Reference)

Safety information for 2-Methyl-3-trifluoromethylaniline

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.