2-Methyl-3-biphenylmethanol
- CAS NO.:76350-90-8
- Empirical Formula: C14H14O
- Molecular Weight: 198.26
- MDL number: MFCD00134200
- EINECS: 1312995-182-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-05 19:05:58
What is 2-Methyl-3-biphenylmethanol?
Description
2-Methyl-3-biphenylmethanol is a pharmaceutical intermediate and organic chemical synthesis reagent, which can be used in the preparation of drugs such as Bifenthrin and PD-L1 inhibitors, and also in the synthesis of other organic compounds such as 2-methyl-3-phenylphenethylboronic acid pinacol ester, biphenyl-1,2,3-triazole couplings and biphenyl alcohols.
Chemical properties
white to light yellow crystal powde
The Uses of 2-Methyl-3-biphenylmethanol
Bifenthrin intermediate.
What are the applications of Application
2-Methyl-3-biphenylmethanol is an intermediate of Bifenthrin
Synthesis
Carrying out a Suzuki coupling reaction between 3-bromo-2-methylbenzoic acid and phenyl substituted boric acid or phenyl substituted borate to obtain 3-phenyl-2-methylbenzoic acid, and then carrying out a reduction reaction to obtain 2-Methyl-3-biphenylmethanol, wherein the Suzuki coupling reaction is carried out at 10-150 DEG C for 1-12 hours under the action of an alkali. 3-phenyl-2-methylbenzoic acid can be directly reduced with a reducing agent such as borane and lithium aluminium hydride to obtain 2-Methyl-3-biphenylmethanol.
Properties of 2-Methyl-3-biphenylmethanol
Melting point: | 73-76 °C(lit.) |
Boiling point: | 330.9±11.0 °C(Predicted) |
Density | 1.072±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,Room Temperature |
solubility | Chloroform (Slightly), Methanol (Slightly) |
form | Solid |
pka | 14.28±0.10(Predicted) |
color | White to Off-White |
CAS DataBase Reference | 76350-90-8(CAS DataBase Reference) |
EPA Substance Registry System | [1,1'-Biphenyl]-3-methanol, 2-methyl- (76350-90-8) |
Safety information for 2-Methyl-3-biphenylmethanol
Computed Descriptors for 2-Methyl-3-biphenylmethanol
InChIKey | BGTLHJPGBIVQLJ-UHFFFAOYSA-N |
Abamectin manufacturer
Aether Industries Limited
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