2-METHYL-1-INDANONE

CAS NO.：17496-14-9
Empirical Formula: C10H10O
Molecular Weight: 146.19
MDL number: MFCD00192303
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 2-METHYL-1-INDANONE?

Chemical properties

Pale yellow liquid

The Uses of 2-METHYL-1-INDANONE

2-Methyl-1-indanone may be used as a starting material in the synthesis of β-benzocycloalkenone. It may be used in the synthesis of the following:

cyclohex-2-en-1-yl 2-methyl-1H-inden-3-yl carbonate
2-hydroxy-2-methyl-1-indanone
O-alkoxycarbonylation of lithium enolates

Synthesis Reference(s)

The Journal of Organic Chemistry, 46, p. 3758, 1981 DOI: 10.1021/jo00331a046
Tetrahedron Letters, 29, p. 2183, 1988 DOI: 10.1016/S0040-4039(00)86705-2

General Description

2-Methyl-1-indanone, a α-benzocycloalkenone, is a derivative of 1-indanone. Its synthesis has been reported. The enzymatic dynamic kinetic resolution (DKR) of racemic 2-methyl-1-indanone has been studied. The asymmetric α-arylation and hydroxymethylation of 2-methyl-1-indanone has been reported. It participated in the synthesis of 2-methyl-6-carboxyazulene.

Properties of 2-METHYL-1-INDANONE

Melting point:	47-47.5 °C
Boiling point:	93-95 °C4 mm Hg(lit.)
Density	1.064 g/mL at 25 °C(lit.)
refractive index	n20/D 1.555(lit.)
Flash point:	>230 °F
storage temp.	Sealed in dry,Room Temperature
color	Yellow

Safety information for 2-METHYL-1-INDANONE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.