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HomeProduct name list2-Methoxypyrazine

2-Methoxypyrazine

  • CAS NO.:3149-28-8
  • Empirical Formula: C5H6N2O
  • Molecular Weight: 110.11
  • MDL number: MFCD00006126
  • EINECS: 221-579-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:08:52
2-Methoxypyrazine Structural

What is 2-Methoxypyrazine?

Description

Methoxypyrazine has an odor threshold of 700 ppb in water. Methoxypyrazine may be prepared from 2-hydroxypyrazine by various routes.

Chemical properties

Colorless liquid

Chemical properties

Methoxypyrazine has a sweet, nutty, cocoa odor. Methoxypyrazine contributes a distinctive “green, capsicum (bell pepper), herbaceous and earthy” aroma that is quite characteristic of certain wines, such as sauvignon blanc and cabernet sauvignon.

Occurrence

Present at ultra-trace levels in sauvignon blanc and cabernet sauvignon grapes and wine. Methoxypyrazine contributes a distinctive wine aroma, even at low parts per trillion levels. Also reported found in cooked beef, cocoa, malt and krill.

Preparation

From 2-hydroxypyrazine by various routes.

Definition

ChEBI: Methoxypyrazine is an aromatic ether and a member of pyrazines.

Aroma threshold values

700 ppb in water

Safety Profile

Skin and eye irritant. When heated to decomposition it emits toxic fumes of NOx.

Properties of 2-Methoxypyrazine

Boiling point: 60-61 °C/29 mmHg (lit.)
Density  1.14 g/mL at 25 °C (lit.)
refractive index  n20/D 1.509(lit.)
FEMA  3302 | METHOXYPYRAZINE
Flash point: 114 °F
storage temp.  Sealed in dry,Room Temperature
form  clear liquid
pka 0.53±0.10(Predicted)
Specific Gravity 1.140
color  Colorless to Almost colorless
Odor at 1.00 % in dipropylene glycol. sweet nutty cocoa
JECFA Number 787
BRN  2241
CAS DataBase Reference 3149-28-8(CAS DataBase Reference)
NIST Chemistry Reference Pyrazine, methoxy-(3149-28-8)
EPA Substance Registry System Pyrazine, methoxy- (3149-28-8)

Safety information for 2-Methoxypyrazine

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H226:Flammable liquids
H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H318:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Methoxypyrazine

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