2-Isobutylthiazole

CAS NO.：18640-74-9
Empirical Formula: C7H11NS
Molecular Weight: 141.23
MDL number: MFCD00005334
EINECS: 242-470-1
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-21 17:11:28

What is 2-Isobutylthiazole?

Description

2-Isobutylthiazole has an odor of tomato leaves. Synthesized via cyclization of aliphatic amides with a,p-dibromo ether.

Chemical properties

Colorless to light yellow liqui

Chemical properties

2-Isobutylthiazole has a tomato leaf odor.

Occurrence

Reportedly identified as the odorous component of tomatoes and in processed tomatoes.

Definition

ChEBI: A 1,3-thiazole in which the hydrogen at position 2 has been replaced by an isobutyl group. A food flavour component with a green note that adds the characteristics of ripe tomatoes. Used in blackcurrent, papaya, melon, raspberry, and roast beef flavours, i also enhances the flavour of fresh lime.

Preparation

By cyclization of aliphatic amides with α,β-dibromo ether.

Aroma threshold values

Detection: 3.5 ppb

Properties of 2-Isobutylthiazole

Boiling point:	180 °C (lit.)
Density	0.995 g/mL at 25 °C (lit.)
refractive index	n20/D 1.495(lit.)
FEMA	3134 \| 2-ISOBUTYLTHIAZOLE
Flash point:	136 °F
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform (Sparingly), Methanol (Slightly)
form	clear liquid
pka	3.24±0.10(Predicted)
Specific Gravity	0.995
color	Light orange to Yellow to Green
Odor	tomato (leaf) odor
JECFA Number	1034
BRN	507823
CAS DataBase Reference	18640-74-9(CAS DataBase Reference)
NIST Chemistry Reference	2-Isobutylthiazole(18640-74-9)
EPA Substance Registry System	Thiazole, 2-(2-methylpropyl)- (18640-74-9)

Safety information for 2-Isobutylthiazole

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.