2-IODO-2-METHYLPROPANE
Synonym(s):tert-Butyl iodide
- CAS NO.：558-17-8
- Empirical Formula: C4H9I
- Molecular Weight: 184.02
- MDL number: MFCD00001068
- EINECS: 209-190-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 13:37:16
What is 2-IODO-2-METHYLPROPANE?
Chemical properties
deep brown liquid
The Uses of 2-IODO-2-METHYLPROPANE
2-Iodo-2-methylpropane is used as a chemical reagent in organic synthesis. Further, it serves as a pharmaceutical intermediate.
Synthesis Reference(s)
Tetrahedron Letters, 36, p. 609, 1995 DOI: 10.1016/0040-4039(94)02315-3
General Description
2-Iodo-2-methylpropane was degraded by reductive dehalogenation with nickel-aluminum alloy in potassium hydroxide solution.
Purification Methods
Vacuum distillation has been used to obtain a distillate which remained colourless for several weeks at -5o. More extensive treatment has been used by Boggs, Thompson and Crain [J Phys Chem 61 625 1957] who washed with aqueous NaHSO3 solution to remove free iodine, dried this for 1hour over Na2SO3 at 0o, and purified it by four or five successive partial freezings of the liquid to obtain colourless material and was stored at -78o with Ag wool. [Beilstein 1 IV 300.]
Properties of 2-IODO-2-METHYLPROPANE
| Melting point: | −38 °C(lit.) |
| Boiling point: | 99-100 °C(lit.) |
| Density | 1.544 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 46 °F |
| storage temp. | 2-8°C |
| solubility | Miscible with ethanol and ether. |
| form | clear liquid to cloudy liquid |
| color | Colorless to Light yellow to Light orange |
| Sensitive | Light Sensitive |
| BRN | 505950 |
| Dielectric constant | 8.4199999999999999 |
| Stability: | Stable, but may discolour upon exposure to light. Highly flammable. Incompatible with strong bases, strong oxidizing agents. |
| CAS DataBase Reference | 558-17-8(CAS DataBase Reference) |
| EPA Substance Registry System | Propane, 2-iodo-2-methyl- (558-17-8) |
Safety information for 2-IODO-2-METHYLPROPANE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07  Environment GHS09 |
| GHS Hazard Statements |
H225:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H400:Hazardous to the aquatic environment, acute hazard |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P273:Avoid release to the environment. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-IODO-2-METHYLPROPANE
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