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HomeProduct name list2-hydroxypropyl-α-cyclodextrin

2-hydroxypropyl-α-cyclodextrin

Synonym(s):α‐HPCD;2‐hydroxypropyl‐α‐CD;2OHpαCD;HPαCD;HP-α-CD

What is 2-hydroxypropyl-α-cyclodextrin?

The Uses of 2-hydroxypropyl-α-cyclodextrin

  • (2-Hydroxypropyl)-α-cyclodextrin can be used as a chiral selector to resolve tryptophan racemate by capillary electrophoresis.
  • It can be used to synthesize biodegradable polyrotaxanes for fabricating blood-contacting devices.
  • Co-polymer based on (2-hydroxypropyl)-α-cyclodextrin cross-linked with polyethylenimine can be used as a gene delivery vector.
  • It can also be used as stabilizer for antibacterial iodine formulations, as it forms a stable inclusion complex with iodine and improves aqueous solubility.

What are the applications of Application

(2-Hydroxypropyl)-α-cyclodextrin is A modified carbohydrate polymer.

General Description

(2-Hydroxypropyl)-α-cyclodextrin is a hydroxyalkyl derivative of cyclodextrin, which is generally used as a substitute of α-cyclodextrin for potential application in food, cosmetics and pharmaceutical industries. It may be used as a parenteral drug carrier on account of its attractive characteristics such as: a greater extent of solubility in water, high dissolution capacity for weakly soluble analytes, and low toxicity.

Properties of 2-hydroxypropyl-α-cyclodextrin

Melting point: 245 °C (dec.)(lit.)
Density  1.39 at 24.6℃
solubility  Soluble in water, methanol, DMF. Insoluble in acetone, chloroform.
form  Solid powder
color  White to off white
optical activity [α]20/D +125°, c = 1 in H2O
EPA Substance Registry System .alpha.-Cyclodextrin, 2-hydroxypropyl ethers (128446-33-3)

Safety information for 2-hydroxypropyl-α-cyclodextrin

Computed Descriptors for 2-hydroxypropyl-α-cyclodextrin

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