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HomeProduct name list2'-HYDROXY-6'-METHOXYACETOPHENONE

2'-HYDROXY-6'-METHOXYACETOPHENONE

  • CAS NO.:703-23-1
  • Empirical Formula: C9H10O3
  • Molecular Weight: 166.17
  • MDL number: MFCD00008732
  • EINECS: 211-872-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-25 18:01:13
2'-HYDROXY-6'-METHOXYACETOPHENONE Structural

What is 2'-HYDROXY-6'-METHOXYACETOPHENONE?

Chemical properties

Yellow crystalline powder

The Uses of 2'-HYDROXY-6'-METHOXYACETOPHENONE

2''-Hydroxy-6''-methoxyacetophenone is useful in the synthesis of an aminopyrazole compound which is used to treat cancer and inhibits Chk1. 2''-Hydroxy-6''-methoxyacetophenone is also used to prepare 5,?4''-?disubstituted flavones, predicted androgen receptor antagonists and naphthopyrazolyl carbothioamides which are anticancer agents.

The Uses of 2'-HYDROXY-6'-METHOXYACETOPHENONE

2′-Hydroxy-6′-methoxyacetophenone was used as starting material in the synthesis of 5-methoxyflavaone. It was also used in synthesis of 5,6-dihydroxyflavone.

Preparation

Preparation by reaction of methyl iodide on 2,6-dihydroxyacetophenone with potassium carbonate in boiling acetone (56%).

Definition

ChEBI: 2'-Hydroxy-6'-methoxyacetophenone is an aromatic ketone.

General Description

An organometallic synthetic route to 2′-hydroxy-6′-methoxyacetophenone was reported.

Properties of 2'-HYDROXY-6'-METHOXYACETOPHENONE

Melting point: 58-60 °C(lit.)
Boiling point: 141 °C16 mm Hg(lit.)
Density  1.158
refractive index  1.5500 (estimate)
Flash point: 141°C/16mm
storage temp.  Sealed in dry,Room Temperature
pka 9.79±0.10(Predicted)
color  Light yellow to yellow
BRN  1869049
CAS DataBase Reference 703-23-1(CAS DataBase Reference)

Safety information for 2'-HYDROXY-6'-METHOXYACETOPHENONE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2'-HYDROXY-6'-METHOXYACETOPHENONE

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