2'-HYDROXY-6'-METHOXYACETOPHENONE
- CAS NO.:703-23-1
- Empirical Formula: C9H10O3
- Molecular Weight: 166.17
- MDL number: MFCD00008732
- EINECS: 211-872-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-25 18:01:13
What is 2'-HYDROXY-6'-METHOXYACETOPHENONE?
Chemical properties
Yellow crystalline powder
The Uses of 2'-HYDROXY-6'-METHOXYACETOPHENONE
2''-Hydroxy-6''-methoxyacetophenone is useful in the synthesis of an aminopyrazole compound which is used to treat cancer and inhibits Chk1. 2''-Hydroxy-6''-methoxyacetophenone is also used to prepare 5,?4''-?disubstituted flavones, predicted androgen receptor antagonists and naphthopyrazolyl carbothioamides which are anticancer agents.
The Uses of 2'-HYDROXY-6'-METHOXYACETOPHENONE
2′-Hydroxy-6′-methoxyacetophenone was used as starting material in the synthesis of 5-methoxyflavaone. It was also used in synthesis of 5,6-dihydroxyflavone.
Preparation
Preparation by reaction of methyl iodide on 2,6-dihydroxyacetophenone with potassium carbonate in boiling acetone (56%).
Definition
ChEBI: 2'-Hydroxy-6'-methoxyacetophenone is an aromatic ketone.
General Description
An organometallic synthetic route to 2′-hydroxy-6′-methoxyacetophenone was reported.
Properties of 2'-HYDROXY-6'-METHOXYACETOPHENONE
Melting point: | 58-60 °C(lit.) |
Boiling point: | 141 °C16 mm Hg(lit.) |
Density | 1.158 |
refractive index | 1.5500 (estimate) |
Flash point: | 141°C/16mm |
storage temp. | Sealed in dry,Room Temperature |
pka | 9.79±0.10(Predicted) |
color | Light yellow to yellow |
BRN | 1869049 |
CAS DataBase Reference | 703-23-1(CAS DataBase Reference) |
Safety information for 2'-HYDROXY-6'-METHOXYACETOPHENONE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2'-HYDROXY-6'-METHOXYACETOPHENONE
Abamectin manufacturer
AVIGYABIOSCIENCES PRIVATE LIMITED
BASR Fine Chemicals Pvt. Ltd.
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