2-Ethyl-2-phenylmalonamide
Synonym(s):2-Ethyl-2-phenylmalondiamide;2-Ethyl-2-phenylpropanediamide;PEMA
- CAS NO.:7206-76-0
- Empirical Formula: C11H14N2O2
- Molecular Weight: 206.24
- MDL number: MFCD00008012
- EINECS: 230-583-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:08:57
What is 2-Ethyl-2-phenylmalonamide?
Chemical properties
White Crystalline Solid
The Uses of 2-Ethyl-2-phenylmalonamide
A metabolite of Primidone
What are the applications of Application
2-Ethyl-2-phenylmalonamide is A metabolite of Primidone
Definition
ChEBI: Phenylethylmalonamide is an amine.
General Description
White crystalline solid.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
2-Ethyl-2-phenylmalonamide is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Health Hazard
SYMPTOMS: Symptoms of exposure to a related compound through ingestion may include sedation, vertigo, dizziness, nausea, vomiting, ataxia, diplopia, nystagmus, an acute feeling of intoxication and, rarely, maculopapular and morbilliform rash, leukopenia, thrombocytopenia, systemic lupus erythematosus, lymphadenopathy, acute psychotic reactions, hemorrhagic disease in the neonate, megaloblastic anemia and osteomalacia.
Fire Hazard
Flash point data for 2-Ethyl-2-phenylmalonamide are not available. 2-Ethyl-2-phenylmalonamide is probably combustible.
Properties of 2-Ethyl-2-phenylmalonamide
Melting point: | 120°C |
Boiling point: | 440.9±45.0 °C(Predicted) |
Density | 1.183±0.06 g/cm3(Predicted) |
Flash point: | 113 °C |
storage temp. | Refrigerator |
solubility | DMSO (Slightly), Methanol (Slightly) |
pka | 14.98±0.50(Predicted) |
form | Solid |
color | White to Off-White |
Water Solubility | <0.01 g/100 mL at 18 ºC |
Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. |
NIST Chemistry Reference | Propanediamide, 2-ethyl-2-phenyl-(7206-76-0) |
EPA Substance Registry System | 2-Phenyl-2-ethylmalonamide (7206-76-0) |
Safety information for 2-Ethyl-2-phenylmalonamide
Computed Descriptors for 2-Ethyl-2-phenylmalonamide
2-Ethyl-2-phenylmalonamide manufacturer
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