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HomeProduct name list2-Deoxy-D-ribose

2-Deoxy-D-ribose

Synonym(s):2-Deoxy-D-arabinose;2-Deoxy-D-erythropentose;Thyminose

  • CAS NO.:533-67-5
  • Empirical Formula: C5H10O4
  • Molecular Weight: 134.13
  • MDL number: MFCD00135904
  • EINECS: 208-573-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-04-09 22:15:29
2-Deoxy-D-ribose Structural Picture

What is 2-Deoxy-D-ribose?

Description

2-deoxy-D-Ribose is a reducing sugar formed as a degradation product during metabolism of thymidine by thymidine phosphorylase. It increases levels of reactive oxygen species (ROS) in HL-60 human leukemia cells when used at a concentration of 15 mM. 2-deoxy-D-Ribose (10 μM) induces tubulogenesis and migration of bovine aortic endothelial (BAE) cells. Topical administration of 2-deoxy-D-ribose increases blood vessel formation and accelerates wound healing in a rat full-thickness cutaneous wound model.

The Uses of 2-Deoxy-D-ribose

2-Deoxy-D-ribose is used as a precursor to deoxyribonucleic acid. It induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Further, it is used in the synthesis of optically active dipyrrolyl alkanols from pyrroles on the surface of montmorillonite KSF clay.

Properties of 2-Deoxy-D-ribose

Melting point: 89-90 °C(lit.)
Boiling point: 167.23°C (rough estimate)
Density  1.0590 (rough estimate)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated)
form  Crystalline Powder
color  White to slightly yellow
Water Solubility  soluble
Sensitive  Hygroscopic

Safety information for 2-Deoxy-D-ribose

Signal word Warning
Pictogram(s)

Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H332:Acute toxicity,inhalation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Deoxy-D-ribose

InChIKey ASJSAQIRZKANQN-CRCLSJGQSA-N

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