2-Deoxy-D-ribose
Synonym(s):2-Deoxy-D -arabinose;2-Deoxy-D -erythropentose;Thyminose
- CAS NO.:533-67-5
- Empirical Formula: C5H10O4
- Molecular Weight: 134.13
- MDL number: MFCD00135904
- EINECS: 208-573-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-09 22:15:29
What is 2-Deoxy-D-ribose?
Description
2-deoxy-D-Ribose is a reducing sugar formed as a degradation product during metabolism of thymidine by thymidine phosphorylase. It increases levels of reactive oxygen species (ROS) in HL-60 human leukemia cells when used at a concentration of 15 mM. 2-deoxy-D-Ribose (10 μM) induces tubulogenesis and migration of bovine aortic endothelial (BAE) cells. Topical administration of 2-deoxy-D-ribose increases blood vessel formation and accelerates wound healing in a rat full-thickness cutaneous wound model.
The Uses of 2-Deoxy-D-ribose
2-Deoxy-D-ribose is used as a precursor to deoxyribonucleic acid. It induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Further, it is used in the synthesis of optically active dipyrrolyl alkanols from pyrroles on the surface of montmorillonite KSF clay.
Properties of 2-Deoxy-D-ribose
Melting point: | 89-90 °C(lit.) |
Boiling point: | 167.23°C (rough estimate) |
Density | 1.0590 (rough estimate) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated) |
form | Crystalline Powder |
color | White to slightly yellow |
Water Solubility | soluble |
Sensitive | Hygroscopic |
Safety information for 2-Deoxy-D-ribose
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Deoxy-D-ribose
InChIKey | ASJSAQIRZKANQN-CRCLSJGQSA-N |
Abamectin manufacturer
Vardhaman P Golechha
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