2-Chlorobenzothiazole
- CAS NO.：615-20-3
- Empirical Formula: C7H4ClNS
- Molecular Weight: 169.63
- MDL number: MFCD00005776
- EINECS: 210-415-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is 2-Chlorobenzothiazole?
Chemical properties
CLEAR YELLOW TO YELLOW-BROWNISH LIQUID
The Uses of 2-Chlorobenzothiazole
2-Chlorobenzothiazole was used in the synthesis of:
- (RS)- and (S)-lubeluzole
- (1,3-benzothiazol-2-yl) amino-9-(10H)-acridinone derivatives
- 4H-thieno[2′,3′:4,5]pyrimido[2,1-b]benzothiazole derivatives
The Uses of 2-Chlorobenzothiazole
2-Chloro-1,3-benzothiazole is used in the synthesis of CBTs which are good building blocks for bioluminescent compounds for imaging.
Purification Methods
It is purified by fractional distillation in vacuo. The 2-chloro-3-methylbenzothiazolinium 2,4-dinitrobenzenesulfonate crystallises from Ac2O, m 162-163o(dec). [Young & Amstutz J Am Chem Soc 73 4773 1951, Brower et al. J Org Chem 19 1830 1954, Hunter & Jones J Chem Soc 2190 1930, Beilstein 27 H 44, 27 II 18, 27 III/IV 1072.]
Properties of 2-Chlorobenzothiazole
| Melting point: | 21-23 °C (lit.) |
| Boiling point: | 141 °C/30 mmHg (lit.) |
| Density | 1.303 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Liquid |
| pka | -0.23±0.10(Predicted) |
| Specific Gravity | 1.3711.303 |
| color | Clear yellow to yellow-brownish |
| Water Solubility | insoluble |
| BRN | 116316 |
| CAS DataBase Reference | 615-20-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzothiazole, 2-chloro-(615-20-3) |
| EPA Substance Registry System | 2-Chlorobenzothiazole (615-20-3) |
Safety information for 2-Chlorobenzothiazole
| Signal word | Warning |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P321:Specific treatment (see … on this label). P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for 2-Chlorobenzothiazole
New Products
3-Iodophenylacetic acid 3-Pyridineacetonitrile, α-hydroxy- 2-Propanamine, 1-chloro-, hydrochloride (9CI) 3-(hexyloxy)-4-(pyridin-3-yl)-1,2,5-thiadiazole 2-Hexyn-1-ol Dibenzo-18-crown-6 Nickel(II) perchlorate hexahydrate, 98% 4-Bromophenylacetonitrile, 95% 3-Bromo-4-fluoroaniline, 97% Sodium tetraborate decahydrate, 98% Palladium(II) acetate, trimer, Pd 99% 4-Bromo-2-chlorotoluene, 97% N N Dimethylformamide Dimethyl Acetal (Dmf Dma) 2,3-Dichloro Benzoyl Cyanide [Side Chain] Bis(2-Chloroethyl) Amine Hydrochloride L-Glutamic Acid Diethyl Ester Hydrochloride 5-(Difluoromethoxy)-2-Mercaptobenzimidazole 1-Ethyl-3-(3-Dimethylaminopropyl)-Carbodiimide Hydrochloride [EDC Hcl] 1,4-Napthoquinone Bromoiodomethane Sodium Bicarbonate Methylene Dichloride (MDC) Ethyl Acetate Indole-3-Carbinol (I3C)Related products of tetrahydrofuran
You may like
-
2-Chlorobenzothiazole CAS 615-20-3View Details
615-20-3 -
2-Chlorobenzothiazole, 99% CAS 615-20-3View Details
615-20-3 -
2-Chlorobenzothiazole CAS 615-20-3View Details
615-20-3 -
17604-74-9 3-Pyridineacetonitrile, α-hydroxy- 98+View Details
17604-74-9 -
Cyclohexane, (2-propynyloxy)- 67967-07-1 98+View Details
67967-07-1 -
2-Propanamine, 1-chloro-, hydrochloride (9CI) 98+View Details
5968-21-8 -
3-Iodophenylacetic acid 1878-69-9 98+View Details
1878-69-9 -
132945-75-6 (S)-1-Boc-3-methanesulfonyloxy-pyrrolidine 98+View Details
132945-75-6
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.