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HomeProduct name list2-Chlorobenzamide

2-Chlorobenzamide

  • CAS NO.:609-66-5
  • Empirical Formula: C7H6ClNO
  • Molecular Weight: 155.58
  • MDL number: MFCD00007973
  • EINECS: 210-195-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-21 22:41:43
2-Chlorobenzamide Structural

What is 2-Chlorobenzamide?

Chemical properties

The substance is an almost white crystalline powder that can be dissolved in solvents such as benzene and toluene.

The Uses of 2-Chlorobenzamide

2-Chlorobenzamide is used to synthesize chlortetracycline and o-chlorobenzoyl isocyanate, which is an intermediate in chlortetracycline synthesis.

General Description

2-Chlorobenzamide is the major degradation product of CCU (1-(2-chlorobenzoyl)-3-(4-chlorophenyl) urea), a new insect growth regulator. It undergoes room temperature Pd-mediated hydrodehalogenations with KF and polymethylhydrosiloxane (PMHS) to yield benzamide. t undergoes reduction with NaBH4 in diglyme at 162°C to yield 2-chlorobenzonitrile.

Synthesis

Prepared by reacting o-chlorobenzoyl chloride with ammonia.

Properties of 2-Chlorobenzamide

Melting point: 142-144 °C(lit.)
Boiling point: 275.0±23.0 °C(Predicted)
Density  1.2187 (rough estimate)
refractive index  1.5618 (estimate)
storage temp.  Sealed in dry,Room Temperature
pka 15.36±0.50(Predicted)
form  powder to crystal
color  White to Almost white
BRN  508510
CAS DataBase Reference 609-66-5(CAS DataBase Reference)
EPA Substance Registry System 2-Chlorobenzamide (609-66-5)

Safety information for 2-Chlorobenzamide

Signal word Warning
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H330:Acute toxicity,inhalation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P320:Specific treatment is urgent (see … on this label).
P330:Rinse mouth.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.
P501:Dispose of contents/container to..…

Computed Descriptors for 2-Chlorobenzamide

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