2-Chloro-N-phenylacetamide

CAS NO.：587-65-5
Empirical Formula: C8H8ClNO
Molecular Weight: 169.61
MDL number: MFCD00018887
EINECS: 209-604-0
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 2-Chloro-N-phenylacetamide?

The Uses of 2-Chloro-N-phenylacetamide

2-Chloro-N-phenylacetamide is used as a reagent in the synthesis of indolylmethylene benzo[h]thiazolo[2,3-b]quinazolinones which exhibit anticancer and antimicrobial activities in vitro.

The Uses of 2-Chloro-N-phenylacetamide

2-Chloro-N-phenylacetamide may be used in the preparation of N,N′-(ethane-1,2-diyl)bis(2-(2-oxo-2-(phenylamino)ethoxy)benzamide), an amide podand. It may also be used to prepare phenylacetamide-based Schiff base ligands by reacting with corresponding hydrazones.

What are the applications of Application

2-Chloro-N-phenylacetamide is a useful biochemical for proteomics research

General Description

2-Chloro-N-phenylacetamide, also known as chloroacetanilide, can be prepared by reacting aniline with chloroacetylchloride in glacial acetic acid. The analysis of its crystal structure shows the presence of N-H...O hydrogen bonds between the molecules.

Properties of 2-Chloro-N-phenylacetamide

Melting point:	136-139 °C (lit.)
Boiling point:	340.0±25.0 °C(Predicted)
Density	1.266±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	12.90±0.70(Predicted)
color	Off-White to Pale Beige
CAS DataBase Reference	587-65-5(CAS DataBase Reference)
EPA Substance Registry System	2-Chloroacetanilide (587-65-5)

Safety information for 2-Chloro-N-phenylacetamide

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.