2-Bromo-6-methylpyridine
- CAS NO.:5315-25-3
- Empirical Formula: C6H6BrN
- Molecular Weight: 172.02
- MDL number: MFCD00040743
- EINECS: 226-173-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-09 13:47:46
What is 2-Bromo-6-methylpyridine?
Chemical properties
Light yellow liquid,store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.
The Uses of 2-Bromo-6-methylpyridine
2-Bromo-6-methylpyridine is a halogenated pyridine derivative used is a building block in the preparation of nitrogen containing heterocyclic compounds.
The Uses of 2-Bromo-6-methylpyridine
2-Bromo-6-methylpyridine may be used in the synthesis of the following:
- 6,6′-dimethyl-2,2′-bipyridine
- 6-methyl-2-pyridyl-2-pyridylmethanone
- 2-methyl-6-(trimethylsilyl)-pyridine
- N,N′-bis-(6-methylpyrid-2-yl)-(1R,2R)-1,2- diaminocyclohexane (cydiampy)
- 2-methyl-6-(trimethylstannanyl)pyridine
- 2-(6-methylpyridin-2-yl)propan-2-ol
- bis[(2-bromo-6-methylpyridinium)hexafluorosilicate] monohydrate
Synthesis Reference(s)
Journal of the American Chemical Society, 76, p. 3168, 1954 DOI: 10.1021/ja01641a017
General Description
2-Bromo-6-methylpyridine is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
Properties of 2-Bromo-6-methylpyridine
Boiling point: | 102-103 °C/20 mmHg (lit.) |
Density | 1.512 g/mL at 25 °C (lit.) |
refractive index | n |
Flash point: | 207 °F |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Chloroform, Ethyl Aceate |
form | Liquid |
pka | 1.51±0.10(Predicted) |
color | Clear colorless to yellow |
Specific Gravity | 1.512 |
Water Solubility | Soluble in chloroform, ethyl aceate. Not miscible or difficult to mix with water. |
BRN | 107322 |
InChI | InChI=1S/C6H6BrN/c1-5-3-2-4-6(7)8-5/h2-4H,1H3 |
CAS DataBase Reference | 5315-25-3(CAS DataBase Reference) |
Safety information for 2-Bromo-6-methylpyridine
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Bromo-6-methylpyridine
InChIKey | SOHDPICLICFSOP-UHFFFAOYSA-N |
SMILES | C1(Br)=NC(C)=CC=C1 |
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