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HomeProduct name list2-Bromo-6-methoxypyridine

2-Bromo-6-methoxypyridine

  • CAS NO.:40473-07-2
  • Empirical Formula: C6H6BrNO
  • Molecular Weight: 188.02
  • MDL number: MFCD00088345
  • EINECS: 628-883-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-27 17:31:30
2-Bromo-6-methoxypyridine Structural

What is 2-Bromo-6-methoxypyridine?

Chemical properties

Light yellow liquid

The Uses of 2-Bromo-6-methoxypyridine

The commercial 2-Bromo-6-methoxypyridine could be used as a starting material to synthesize cyclopenta[b]pyridin-2,5-dione. The overall route consists of a first sequence of regioselective ortho lithiation and methoxycarbonylation followed by Heck vinylation, alkene reduction, cyclization, and decarboxylation[1].

References

[1] Robert, Nicolas , et al. "A convenient synthesis of cyclopenta[b]pyridin-2,5-dione as a non- glycosidic cardiotonic agent." ARKIVOC 2008.7(2008):92-100.

Properties of 2-Bromo-6-methoxypyridine

Boiling point: 206 °C (lit.)
Density  1.53 g/mL at 25 °C (lit.)
refractive index  n20/D 1.559(lit.)
Flash point: 220 °F
storage temp.  Inert atmosphere,Room Temperature
form  Liquid
pka -1.04±0.10(Predicted)
color  Clear colorless to golden
InChI InChI=1S/C6H6BrNO/c1-9-6-4-2-3-5(7)8-6/h2-4H,1H3
CAS DataBase Reference 40473-07-2(CAS DataBase Reference)

Safety information for 2-Bromo-6-methoxypyridine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Bromo-6-methoxypyridine

InChIKey KMODISUYWZPVGV-UHFFFAOYSA-N
SMILES C1(Br)=NC(OC)=CC=C1

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