2-Bromo-3-hydroxy-6-methylpyridine

CAS NO.：23003-35-2
Empirical Formula: C6H6BrNO
Molecular Weight: 188.02
MDL number: MFCD06655956
SAFETY DATA SHEET (SDS)
Update Date: 2024-01-19 11:28:20

What is 2-Bromo-3-hydroxy-6-methylpyridine?

Chemical properties

White solid

Synthesis Reference(s)

Tetrahedron, 61, p. 4569, 2005 DOI: 10.1016/j.tet.2005.03.008

Structure and conformation

In the compound C6H6BrNO (2-Bromo-3-hydroxy-6-methylpyridine), the Br atom is displaced from the pyridine ring mean plane by 0.0948Å, while the hydroxyl O atom and the methyl C atom are displaced by 0.0173 and 0.015Å, respectively. In the crystal, mol-ecules are linked via O—H…N hydrogen bonds, forming chains propagating along the a-axis direction. These chains are linked by C—H?Br hydrogen bonds, forming corrugated two-dimensional networks lying parallel to the ac plane.
2-Bromo-3-hydroxy-6-methylpyridine

Properties of 2-Bromo-3-hydroxy-6-methylpyridine

Melting point:	186-187 °C
Boiling point:	311.8±37.0 °C(Predicted)
Density	1.655±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
pka	4.66±0.10(Predicted)
InChI	InChI=1S/C6H6BrNO/c1-4-2-3-5(9)6(7)8-4/h2-3,9H,1H3

Safety information for 2-Bromo-3-hydroxy-6-methylpyridine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.