2-Anilinoethanol

Synonym(s):N-Phenylethanolamine;2-(Phenylamino)ethanol;2-Anilinoethanol;N-(2-Hydroxyethyl)aniline, N-Phenylethanolamine, 2-(Phenylamino)ethanol

CAS NO.：122-98-5
Empirical Formula: C8H11NO
Molecular Weight: 137.18
MDL number: MFCD00002832
EINECS: 204-588-1
SAFETY DATA SHEET (SDS)
Update Date: 2024-12-18 14:07:02

What is 2-Anilinoethanol?

Chemical properties

CLEAR YELLOW TO BROWN LIQUID

The Uses of 2-Anilinoethanol

N-Phenylethanolamine is used as an intermediate for dyes and other organic compounds. Further, it is used as a substrate for human olfactory uridine 5'-diphospho-glucuronosyltransferase.

The Uses of 2-Anilinoethanol

N-(2-Hydroxyethyl)aniline was employed as substrate for human olfactory UDP-glucuronosyltransferase.

What are the applications of Application

N-(2-Hydroxyethyl)aniline is an amino alcohol for proteomics research

Definition

ChEBI: 2-Anilinoethanol is an aralkylamine.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 11, p. 87, 1968 DOI: 10.1021/jm00307a019
Journal of the American Chemical Society, 74, p. 5514, 1952
Tetrahedron Letters, 10, p. 4555, 1969 DOI: 10.1017/S0009838800024678

Synthesis Reference(s)

Synthetic Communications, 24, p. 1415, 1994 DOI: 10.1080/00397919408011745

Flammability and Explosibility

Not classified

Safety Profile

Poison by skin contact, intraperitoneal, and intravenous routes. Moderately toxic by ingestion. A skin and severe eye irritant. Combustible when exposed to heat or flame. To fight fire, use dry chemical, water mist. When heated to decomposition it emits toxic fumes of NOx.

Properties of 2-Anilinoethanol

Melting point:	-30 °C
Boiling point:	150-152 °C10 mm Hg(lit.)
Density	1.094 g/mL at 25 °C(lit.)
vapor density	>1 (vs air)
vapor pressure	<0.01 mm Hg ( 20 °C)
refractive index	n20/D 1.578(lit.)
Flash point:	>230 °F
storage temp.	Store below +30°C.
solubility	4.5g/l
form	clear liquid
pka	14.39±0.10(Predicted)
color	Colorless to Red to Green
PH	10.2 (10g/l, H2O, 20℃)
explosive limit	1-6.8%(V)
Water Solubility	53 g/L (20 ºC)
BRN	774672
CAS DataBase Reference	122-98-5(CAS DataBase Reference)
NIST Chemistry Reference	Ethanol, 2-(phenylamino)-(122-98-5)
EPA Substance Registry System	Ethanol, 2-(phenylamino)- (122-98-5)

Safety information for 2-Anilinoethanol

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H310:Acute toxicity,dermal H318:Serious eye damage/eye irritation H373:Specific target organ toxicity, repeated exposure H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P262:Do not get in eyes, on skin, or on clothing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P314:Get medical advice/attention if you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.