2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile

CAS NO.：950596-58-4
Empirical Formula: C13H18N2O4
Molecular Weight: 266.29
MDL number: MFCD16619377
EINECS: 1308068-626-2
SAFETY DATA SHEET (SDS)
Update Date: 2023-12-14 20:49:34

What is 2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile?

The Uses of 2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile

2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile is an impurity of Erlotinib (E625008), a EGFR-targeted drug in the treatment of non-small cell lung cancer. EGFR small tyrosine kinase inhibitor that shows most substantial effect on tumor growth inhibition and animal survival.

The Uses of 2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile

2-((4-Chloro-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethanol is an impurity if Erlotinib (E625008) a EGFR-targeted drug in the treatment of non-small cell lung cancer.

Properties of 2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile

Melting point:	73-77 °C
Boiling point:	445.5±45.0 °C(Predicted)
Density	1.17±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	1.85±0.10(Predicted)
color	Pale Beige to Beige

Safety information for 2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.