2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE
- CAS NO.:76180-96-6
- Empirical Formula: C11H10N4
- Molecular Weight: 198.22
- MDL number: MFCD00210316
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE?
Chemical properties
Beige Powder
The Uses of 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE
IQ is highly mutagenic in the Ames test. Investigations have shown that this compound may be present in broiled fish, fried beef, commercial beef extracts and protein pyrolysates
What are the applications of Application
2-Amino-3-methyl-3H-imidazo[4,5-F]quinoline is a highly mutagenic compound
Definition
ChEBI: An imidazoquinoline that is 3H-imidazo[4,5-f]quinoline substituted by a methyl group at position 3 and an amino group at position 2.
Synthesis Reference(s)
Chemical and Pharmaceutical Bulletin, 30, p. 1857, 1982 DOI: 10.1248/cpb.30.1857
Synthetic Communications, 18, p. 973, 1988 DOI: 10.1080/00397918808060881
General Description
Light tan crystalline solid or tan powder.
Air & Water Reactions
2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE is sensitive to light and air. Insoluble in water.
Reactivity Profile
2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE may be sensitive to prolonged exposure to heat. 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE is stable under moderately acidic and alkaline conditions and in cold dilute aqueous solutions when protected from light. 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE is rapidly degraded by dilute hypochlorite.
Health Hazard
ACUTE/CHRONIC HAZARDS: It may emit potentially toxic fumes when involved in a fire.
Fire Hazard
Flash point data for 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE are not available; however, 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE is probably combustible.
Safety Profile
Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx,
Carcinogenicity
IQ is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Properties of 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE
Melting point: | >300 |
Boiling point: | 325.54°C (rough estimate) |
Density | 1.2366 (rough estimate) |
refractive index | 1.4260 (estimate) |
storage temp. | Refrigerator |
solubility | DMSO (Slightly, Heated), Methanol (Slightly) |
form | Solid |
pka | 5.86±0.40(Predicted) |
color | Pale Green to Beige |
IARC | 2A (Vol. Sup 7, 56) 1993 |
EPA Substance Registry System | 2-Amino-3-methylimidazo[4,5-f]quinoline (76180-96-6) |
Safety information for 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE
Signal word | Warning |
Pictogram(s) |
Health Hazard GHS08 |
GHS Hazard Statements |
H341:Germ cell mutagenicity H351:Carcinogenicity |
Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE
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