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HomeProduct name list2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE

2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE

2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE Structural

What is 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE?

Chemical properties

Beige Powder

The Uses of 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE

IQ is highly mutagenic in the Ames test. Investigations have shown that this compound may be present in broiled fish, fried beef, commercial beef extracts and protein pyrolysates

What are the applications of Application

2-Amino-3-methyl-3H-imidazo[4,5-F]quinoline is a highly mutagenic compound

Definition

ChEBI: An imidazoquinoline that is 3H-imidazo[4,5-f]quinoline substituted by a methyl group at position 3 and an amino group at position 2.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 30, p. 1857, 1982 DOI: 10.1248/cpb.30.1857
Synthetic Communications, 18, p. 973, 1988 DOI: 10.1080/00397918808060881

General Description

Light tan crystalline solid or tan powder.

Air & Water Reactions

2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE is sensitive to light and air. Insoluble in water.

Reactivity Profile

2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE may be sensitive to prolonged exposure to heat. 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE is stable under moderately acidic and alkaline conditions and in cold dilute aqueous solutions when protected from light. 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE is rapidly degraded by dilute hypochlorite.

Health Hazard

ACUTE/CHRONIC HAZARDS: It may emit potentially toxic fumes when involved in a fire.

Fire Hazard

Flash point data for 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE are not available; however, 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE is probably combustible.

Safety Profile

Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx,

Carcinogenicity

IQ is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

Properties of 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE

Melting point: >300
Boiling point: 325.54°C (rough estimate)
Density  1.2366 (rough estimate)
refractive index  1.4260 (estimate)
storage temp.  Refrigerator
solubility  DMSO (Slightly, Heated), Methanol (Slightly)
form  Solid
pka 5.86±0.40(Predicted)
color  Pale Green to Beige
IARC 2A (Vol. Sup 7, 56) 1993
EPA Substance Registry System 2-Amino-3-methylimidazo[4,5-f]quinoline (76180-96-6)

Safety information for 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE

Signal word Warning
Pictogram(s)
ghs
Health Hazard
GHS08
GHS Hazard Statements H341:Germ cell mutagenicity
H351:Carcinogenicity
Precautionary Statement Codes P201:Obtain special instructions before use.
P202:Do not handle until all safety precautions have been read and understood.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313:IF exposed or concerned: Get medical advice/attention.
P405:Store locked up.
P501:Dispose of contents/container to..…

Computed Descriptors for 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE

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