2-(2-Hydroxyphenyl)benzothiazole

CAS NO.：3411-95-8
Empirical Formula: C13H9NOS
Molecular Weight: 227.28
MDL number: MFCD00022869
EINECS: 222-299-9
SAFETY DATA SHEET (SDS)
Update Date: 2025-01-27 09:38:02

What is 2-(2-Hydroxyphenyl)benzothiazole?

Chemical properties

Off-white to yellow powder

Definition

ChEBI: 2-(1,3-benzothiazol-2-yl)phenol is a member of the class of benzothiazoles that is 1,3-benzothiazole substituted by a 2-hydroxyphenyl group at position 2. It has a role as a geroprotector. It is a member of phenols and a member of benzothiazoles.

Purification Methods

Recrystallise it several times from aqueous EtOH or dilute AcOH and sublime it. [Itoh & Fujiwara J Am Chem Soc 107 1561 1985, Bogert & Corbitt J Am Chem Soc 48 786 1926, Beilstein 27 II 91.]

Properties of 2-(2-Hydroxyphenyl)benzothiazole

Melting point:	128-132 °C (lit.)
Boiling point:	175-193 °C
Density	1.2168 (rough estimate)
refractive index	1.6800 (estimate)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	Solubility Insoluble in water; soluble in ethanol
form	Solid
pka	8.21(at 25℃)
color	White to Light yellow
PH Range	Non0 uorescence (<9.3) to blue-green 0 uorescence (9.3)
BRN	173026
Major Application	Organic light emitting devices, electroluminescent devices, laser dyes, photography, plastic scintillation applications, herbicides, eyeglass lenses, cosmetics
CAS DataBase Reference	3411-95-8(CAS DataBase Reference)
NIST Chemistry Reference	Phenol, o-(2-benzothiazolyl)-(3411-95-8)
EPA Substance Registry System	Phenol, 2-(2-benzothiazolyl)- (3411-95-8)

Safety information for 2-(2-Hydroxyphenyl)benzothiazole

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.