2-(2-Hydroxyethyl)pyridine
Synonym(s):2-(2-Hydroxyethyl)pyridine;2-(2-Pyridyl)ethanol
- CAS NO.:103-74-2
- Empirical Formula: C7H9NO
- Molecular Weight: 123.15
- MDL number: MFCD00006364
- EINECS: 203-140-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-04 20:11:12
What is 2-(2-Hydroxyethyl)pyridine?
Chemical properties
clear yellow to brown liquid
The Uses of 2-(2-Hydroxyethyl)pyridine
2-(2-Hydroxyethyl)pyridine is a metabolite of the anti-vertigo drug Betahistine. It acts as a reagent for protection of the 5'-phosphate of nucleotides as 2-pyridylethyl (Pet) esters. It is used for carboxyl protection of amino acids. It is also used to cleave such groups as Boc and Fmoc, and also to hydrogenolysis. It was used to prepare mononuclear nickel(II) acetate.
The Uses of 2-(2-Hydroxyethyl)pyridine
2-Pyridineethanol is a metabolite of the anti-vertigo drug Betahistine (B324000).
General Description
2-(2-pyridyl)ethanol derivatives react with the aryl and alkenyl chlorides (palladium-catalyzed reactions) that result in the substitution of the chloro moieties with a 2-pyridylmethyl group.
Properties of 2-(2-Hydroxyethyl)pyridine
Melting point: | -8--7°C |
Boiling point: | 114-116 °C/9 mmHg (lit.) |
Density | 1.093 g/mL at 25 °C (lit.) |
vapor pressure | 1.16-14.1Pa at 25℃ |
refractive index | n |
Flash point: | 199 °F |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Soluble in Chloroform (Slightly), Methanol (Slightly). |
form | Liquid |
pka | 14.49±0.10(Predicted) |
color | Clear yellow to brown |
PH | 8-9 (100g/l, H2O, 20℃) |
Water Solubility | soluble |
Sensitive | Hygroscopic |
BRN | 111205 |
CAS DataBase Reference | 103-74-2(CAS DataBase Reference) |
NIST Chemistry Reference | 2-Pyridineethanol(103-74-2) |
EPA Substance Registry System | 2-Pyridineethanol (103-74-2) |
Safety information for 2-(2-Hydroxyethyl)pyridine
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 2-(2-Hydroxyethyl)pyridine
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