2-(2-aminoethyl)phenol
- CAS NO.:2039-66-9
- Empirical Formula: C8H11NO
- Molecular Weight: 137.18
- MDL number: MFCD00192585
- EINECS: 218-016-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-07-14 17:49:14
What is 2-(2-aminoethyl)phenol ?
Description
2-Hydroxyphenethylamine (also known as phenylethanolamine) is a kind of trace amine found in the brain. It may modulate the sympathetic functions. It has strong cardiovascular activity, and can be used as a drug to produce topical vasoconstriction. Its derivatives are adrenergic agonists and antagonists, and have the potential for the treatment of respiratory diseases.
The Uses of 2-(2-aminoethyl)phenol
2-(2-aminoethyl)phenol is a ortho-hydroxylated phenylethylamine present in urine of patients with affective disorder following (MAO-inhibiting) antidepressant drug treatment. It has been used in studies as a substrate of monoa mine oxidase B and was revealed to be a potential inactivator of MAO-B.
The Uses of 2-(2-aminoethyl)phenol
A ortho-hydroxylated phenylethylamine present in urine of patients with affective disorder following (MAO-inhibiting) antidepressant drug treatment. It has been used in studies as a substrate of monoamine oxidase B and was revealed to be a potential inactivator of MAO-B.
Definition
ChEBI: 2-(2-aminoethyl)phenol is a primary amine.
Synthesis Reference(s)
The Journal of Organic Chemistry, 41, p. 2502, 1976 DOI: 10.1021/jo00876a038
References
https://en.wikipedia.org/wiki/Phenylethanolamine
Biggadike, Keith, et al. "PHENYLETHANOLAMINE DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASES." WO, EP 1556340 A1. 2005.
https://pubchem.ncbi.nlm.nih.gov/compound/2-Amino-1-phenylethanol#section=Top
Properties of 2-(2-aminoethyl)phenol
Melting point: | 113-115 °C |
Boiling point: | 258.0±15.0 °C(Predicted) |
Density | 1.103±0.06 g/cm3(Predicted) |
storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
pka | 9.41±0.35(Predicted) |
Safety information for 2-(2-aminoethyl)phenol
Computed Descriptors for 2-(2-aminoethyl)phenol
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