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HomeProduct name list2-(2-aminoethyl)phenol

2-(2-aminoethyl)phenol

  • CAS NO.:2039-66-9
  • Empirical Formula: C8H11NO
  • Molecular Weight: 137.18
  • MDL number: MFCD00192585
  • EINECS: 218-016-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-07-14 17:49:14
2-(2-aminoethyl)phenol  Structural

What is 2-(2-aminoethyl)phenol ?

Description

2-Hydroxyphenethylamine (also known as phenylethanolamine) is a kind of trace amine found in the brain. It may modulate the sympathetic functions. It has strong cardiovascular activity, and can be used as a drug to produce topical vasoconstriction. Its derivatives are adrenergic agonists and antagonists, and have the potential for the treatment of respiratory diseases.

The Uses of 2-(2-aminoethyl)phenol

2-(2-aminoethyl)phenol is a ortho-hydroxylated phenylethylamine present in urine of patients with affective disorder following (MAO-inhibiting) antidepressant drug treatment. It has been used in studies as a substrate of monoa mine oxidase B and was revealed to be a potential inactivator of MAO-B.

The Uses of 2-(2-aminoethyl)phenol

A ortho-hydroxylated phenylethylamine present in urine of patients with affective disorder following (MAO-inhibiting) antidepressant drug treatment. It has been used in studies as a substrate of monoamine oxidase B and was revealed to be a potential inactivator of MAO-B.

Definition

ChEBI: 2-(2-aminoethyl)phenol is a primary amine.

Synthesis Reference(s)

The Journal of Organic Chemistry, 41, p. 2502, 1976 DOI: 10.1021/jo00876a038

References

https://en.wikipedia.org/wiki/Phenylethanolamine
Biggadike, Keith, et al. "PHENYLETHANOLAMINE DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASES." WO, EP 1556340 A1. 2005.
https://pubchem.ncbi.nlm.nih.gov/compound/2-Amino-1-phenylethanol#section=Top

Properties of 2-(2-aminoethyl)phenol

Melting point: 113-115 °C
Boiling point: 258.0±15.0 °C(Predicted)
Density  1.103±0.06 g/cm3(Predicted)
storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C
pka 9.41±0.35(Predicted)

Safety information for 2-(2-aminoethyl)phenol

Computed Descriptors for 2-(2-aminoethyl)phenol

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