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HomeProduct name list2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL

2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL

2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL Structural

What is 2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL?

Description

Benzyl-PEG7-alcohol is a PEG chain containing a benzyl protecing group and a primary alcohol group. The benzyl is an alcohol protecting group and can be removed via hydrogenolysis. The alcohol group can react to further derivatize the compound. The hydrophilic PEG chains increase the water solubility of the compound in aqueous media. Longer PEG chains have better water solubility properties relative to shorter PEG chains.

Biological Activity

BnO-PEG6-OH is a non-cleavable ADC linker containing 6-unit PEG, which can be used to synthesize antibody drug conjugates (ADC). It is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.

Properties of 2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL

Boiling point: 473.6±40.0 °C(Predicted)
Density  1.097±0.06 g/cm3(Predicted)
refractive index  1.4920 to 1.4960
solubility  Soluble in DMSO, DCM, DMF
form  clear liquid
pka 14.36±0.10(Predicted)
color  Colorless to Light yellow
CAS DataBase Reference 24342-68-5

Safety information for 2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL

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