N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE
- CAS NO.：359860-27-8
- Empirical Formula: C18H34N4O5S
- Molecular Weight: 418.55
- MDL number: MFCD09952640
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE?
Description
Biotin-PEG3-amine is reactive with NHS ester or carboxylic acid in the presence of EDC or HATU. PEG3 increases aqueous solubility of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.
The Uses of N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE
(+)-Biotinyl 3,6,9-Trioxaundecanediamine is a biotin derivative and is used as a reagent in the synthesis of a potent, covalent BTK inhibitor for B-cell lymphoma.
Properties of N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE
| Melting point: | 101-103°C |
| Boiling point: | 705.8±60.0 °C(Predicted) |
| Density | 1.166±0.06 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Methanol (Slightly) |
| form | Solid |
| pka | 13.90±0.40(Predicted) |
| color | Pale Yellow to Pale Beige |
| CAS DataBase Reference | 359860-27-8 |
Safety information for N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
Computed Descriptors for N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE
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