(1R,2R)-(-)-1,2-Diaminocyclohexane

Synonym(s):(1R)-trans-1,2-Cyclohexanediamine

CAS NO.：20439-47-8
Empirical Formula: C6H14N2
Molecular Weight: 114.19
MDL number: MFCD00062985
EINECS: 606-556-6
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-04 20:04:50

(1R,2R)-(-)-1,2-Diaminocyclohexane Structural

What is (1R,2R)-(-)-1,2-Diaminocyclohexane?

Chemical properties

white to light yellow crystal powder

The Uses of (1R,2R)-(-)-1,2-Diaminocyclohexane

(1R,2R)-(-)-1,2-Diaminocyclohexane can be used as a building block for chiral ligands.

The Uses of (1R,2R)-(-)-1,2-Diaminocyclohexane

suzuki reaction

The Uses of (1R,2R)-(-)-1,2-Diaminocyclohexane

(1R,2R)-(-)-1,2-Diaminocyclohexane is a versatile ligand for the formation of metal complexes. Used in the synthesis of chiral tropocoronands which have potential utility in asymmetric catalysis.

What are the applications of Application

(1R,2R)-(?)-1,2-Diaminocyclohexane is a versatile ligand used for the formation of metal complexes

Purification Methods

Distil or recrystallise the diamine from pet ether under N2 or Ar. Store it as above. The 1R,2R-base L-tartrate salt has M 264.3, m 2 7 3o and [ ] D +12.5o (c 4, H2O), and can be used to purfy and/or optically enrich the free base. [Beilstein 13 III 6, and references below.]

Properties of (1R,2R)-(-)-1,2-Diaminocyclohexane

Melting point:	41-45 °C
Boiling point:	86-88°C 23mm
alpha	-24.5 º (c=5 1 N HCl 20 º 26.5 ºC)
Density	0.931
refractive index	-25.5 ° (C=5, 1mol/L HCl)
Flash point:	169 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Aqueous Acid (Slightly), Chloroform (Sparingly), Methanol (Slightly)
form	Crystalline Low Melting Solid
pka	10.76±0.70(Predicted)
color	White to pale yellow
optical activity	[α]20/D 25°, c = 5 in 1 M HCl
Water Solubility	Soluble in water.
Sensitive	Air Sensitive
BRN	4780911
Stability:	Air Sensitive
CAS DataBase Reference	20439-47-8(CAS DataBase Reference)

Safety information for (1R,2R)-(-)-1,2-Diaminocyclohexane

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.