Cyclobutanecarboxylic acid
- CAS NO.:3721-95-7
- Empirical Formula: C5H8O2
- Molecular Weight: 100.12
- MDL number: MFCD00001323
- EINECS: 223-072-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-24 21:11:45
What is Cyclobutanecarboxylic acid?
Chemical properties
CLEAR COLOURLESS TO SLIGHTLY AMBER LIQUID
The Uses of Cyclobutanecarboxylic acid
Cyclobutanecarboxylic acid is used in water treatment, row materials for sodium fluosilicate potassium fluosilicateammonium fluosilicatecopper fluosilicatebarium fluosilicate and other fluosilicates and silicic tetrafluoride. It is also used in refining lead of electrolysis, as mordant and in the treatment of metal surface.
Preparation
Cyclobutanecarboxylic acid synthesis: Put 1,1-Cyclobutanedicarboxylic acid into a distillation device for heating, decarboxylate at about 160°C to release carbon dioxide, then heat for distillation, collect 189-195°C fractions as crude product, and re-distill to obtain the finished product cyclobutanecarboxylic acid. Yield 86%-91%.
Synthesis Reference(s)
The Journal of Organic Chemistry, 22, p. 1680, 1957 DOI: 10.1021/jo01363a041
Purification Methods
Dissolve the acid in aqueous HCO 3 then acidify with HCl and extract it into Et2O, wash with H2O, dry (Na2SO4), concentrate to a small volume, then distil it through a glass helices packed column. The S-benzylisothiuronium salt has m 176o (from EtOH), the anilide has m 112.5-113o, and the p-toluide has m 123o. [Payne & Smith J Org Chem 22 1680 1957, Kantaro & Gunning J Am Chem Soc 73 480 1951, Stodola & Heisig Org Synth Coll Vol III 213 1955, Beilstein 9 H 5.]
Properties of Cyclobutanecarboxylic acid
Melting point: | −7.5 °C(lit.) |
Boiling point: | 195 °C(lit.) |
Density | 1.047 g/mL at 25 °C(lit.) |
refractive index | n |
Flash point: | 183 °F |
storage temp. | Sealed in dry,Room Temperature |
solubility | soluble in Chloroform, Methanol |
pka | pK1:4.785 (25°C) |
form | Liquid |
color | Clear colorless to yellow |
Specific Gravity | 1.047 |
Water Solubility | Slightly soluble in water. |
BRN | 1816777 |
CAS DataBase Reference | 3721-95-7(CAS DataBase Reference) |
NIST Chemistry Reference | Cyclobutane carboxylic acid(3721-95-7) |
EPA Substance Registry System | Cyclobutanecarboxylic acid (3721-95-7) |
Safety information for Cyclobutanecarboxylic acid
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 |
GHS Hazard Statements |
H314:Skin corrosion/irritation |
Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Cyclobutanecarboxylic acid
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