1,9-DIDEOXYFORSKOLIN
Synonym(s):7β-Acetoxy-6β-hydroxy-8,13-epoxy-labd-14-en-11-one;7β-Acetoxy-8,13-epoxy-6β-hydroxy-labd-14-en-11-one;Forskolin, 1,9-Dideoxy-, Coleus forskohlii - CAS 64657-18-7 - Calbiochem
- CAS NO.：64657-18-7
- Empirical Formula: C22H34O5
- Molecular Weight: 378.5
- MDL number: MFCD28125819
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:02:03
What is 1,9-DIDEOXYFORSKOLIN?
Description
Forskolin is a naturally-occurring diterpene that activates adenylyl cyclase through its catalytic subunit and is commonly used to raise levels of cAMP in a wide variety of intact cells and tissue preparations. 1,9-dideoxy Forskolin is an analog of forskolin that interacts with, but does not activate, adenylyl cyclase.
The Uses of 1,9-DIDEOXYFORSKOLIN
1,9-Dideoxyforkskolin does not activate adenylyl cyclase and is an inactive analog of Forskolin (F701800), a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP.
What are the applications of Application
1,9-Dideoxyforskolin is a Forskolin analog that does not activate adenylate cyclase
Definition
ChEBI: A labdane diterpenoid that is the 1,9-dideoxy derivative of forskolin.
Properties of 1,9-DIDEOXYFORSKOLIN
| Melting point: | 149-150℃ |
| storage temp. | −20°C |
| solubility | methanol: 28 mg/mL |
| form | solid |
| color | white |
| optical activity | [α]26/D +93.6°, c = 6.12 in chloroform(lit.) |
Safety information for 1,9-DIDEOXYFORSKOLIN
Computed Descriptors for 1,9-DIDEOXYFORSKOLIN
| InChIKey | ZKZMDXUDDJYAIB-OJPJTMFRSA-N |
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