1,8-Octanediol

Synonym(s):Octamethylene glycol

CAS NO.：629-41-4
Empirical Formula: C8H18O2
Molecular Weight: 146.23
MDL number: MFCD00002989
EINECS: 211-090-8
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-24 21:11:45

What is 1,8-Octanediol?

Chemical properties

colorless to white crystals or flakes. soluble in ethanol, insoluble in water, ether, light gasoline.

The Uses of 1,8-Octanediol

As a monomer, 1,8-Octanediol is used in the synthesis of polymers polyesters and polyurethane.

What are the applications of Application

1,8-Octanediol is used in cosmetics, perfumes, ink, essence and in UV coating. It acts as a precursor in the synthesis of polymer and in the manufacture of pharmaceuticals. 1,8-Octanediol can undergo:
Polycondensation with citric acid to form biodegradable poly(1,8-octanediol citrate)(POC) crosslinked bioelastomer which can be blended with various additives.
Fischer esterification with dicarboxylic acids to form diol-based macromers.

What are the applications of Application

1,8-Octanediol is a monomer used in polymer synthesis

Preparation

1,8-Octanediol is synthesized by hydrogenation reduction under high temperature and high pressure using diethyl suberate as raw material and copper-chromium oxide as catalyst.

Definition

ChEBI: Octane-1,8-diol is an octanediol.

Purification Methods

Recrystallise the diol from EtOH and distil it in a vacuum. [Beilstein 1 IV 2592.]

Properties of 1,8-Octanediol

Melting point:	57-61 °C (lit.)
Boiling point:	172 °C/20 mmHg (lit.)
Density	1,053g/cm
refractive index	1,438-1,44
Flash point:	148°C
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Powder or Crystalline
pka	14.89±0.10(Predicted)
color	Off-white to pale yellow
Water Solubility	Soluble in water and methanol.
BRN	1633499
InChI	InChI=1S/C8H18O2/c9-7-5-3-1-2-4-6-8-10/h9-10H,1-8H2
CAS DataBase Reference	629-41-4(CAS DataBase Reference)
NIST Chemistry Reference	1,8-Octanediol(629-41-4)

Safety information for 1,8-Octanediol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.