17BETA-ESTRADIOL, CYCLODEXTRIN-ENCAPSULATED

Synonym(s):Cyclodextrin-encapsulated 17β-estradiol

Empirical Formula: C64H102O37
Molecular Weight: 1463.47
MDL number: MFCD00133134
Update Date: 2023-04-23 13:52:06

17BETA-ESTRADIOL, CYCLODEXTRIN-ENCAPSULATED Structural

What is 17BETA-ESTRADIOL, CYCLODEXTRIN-ENCAPSULATED?

The Uses of 17BETA-ESTRADIOL, CYCLODEXTRIN-ENCAPSULATED

β-estradiol has been used:

to culture differentiated adipocytes
for estradiol treatment in rats
for oocyte maturation in vitro

β-Estradiol is used to study cell differentiation and transformations (tumorigenicity). This product is not recommended for use in binding assays.

General Description

β-estradiol is a natural human?estrogen. It is vital for the growth of breast and reproductive epithelia, maturation of long bones and development of secondary sexual characteristics. Estradiol is produced by immature germ cells, spermatozoa, Leydig cells and Sertoli cells. β-estradiol acts as a menopausal hormones. It is involved in replacement therapy for female hypogonadism or primary ovarian failure. Reduced levels of β-estradiol are linked to heart disease and osteoporosis. Estradiol plays a critical role in proliferation, modulation of ion transport and control of apoptosis in Sertoli cells. It maintains sperm concentration, motility and morphology.

Properties of 17BETA-ESTRADIOL, CYCLODEXTRIN-ENCAPSULATED

solubility

H₂O: 25 mg/mL, may be clear to slightly hazy

Safety information for 17BETA-ESTRADIOL, CYCLODEXTRIN-ENCAPSULATED

Signal word	Danger
Pictogram(s)	Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H351:Carcinogenicity H362:Reproductive toxicity, effects on or via lactation H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P202:Do not handle until all safety precautions have been read and understood. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P263:Avoid contact during pregnancy/while nursing. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P273:Avoid release to the environment. P308+P313:IF exposed or concerned: Get medical advice/attention.