17BETA-ESTRADIOL, CYCLODEXTRIN-ENCAPSULATED
Synonym(s):Cyclodextrin-encapsulated 17β-estradiol
- Empirical Formula: C64H102O37
- Molecular Weight: 1463.47
- MDL number: MFCD00133134
- Update Date: 2023-04-23 13:52:06
What is 17BETA-ESTRADIOL, CYCLODEXTRIN-ENCAPSULATED?
The Uses of 17BETA-ESTRADIOL, CYCLODEXTRIN-ENCAPSULATED
β-estradiol has been used:
- to culture differentiated adipocytes
- for estradiol treatment in rats
- for oocyte maturation in vitro
General Description
β-estradiol is a natural human?estrogen. It is vital for the growth of breast and reproductive epithelia, maturation of long bones and development of secondary sexual characteristics. Estradiol is produced by immature germ cells, spermatozoa, Leydig cells and Sertoli cells. β-estradiol acts as a menopausal hormones. It is involved in replacement therapy for female hypogonadism or primary ovarian failure. Reduced levels of β-estradiol are linked to heart disease and osteoporosis. Estradiol plays a critical role in proliferation, modulation of ion transport and control of apoptosis in Sertoli cells. It maintains sperm concentration, motility and morphology.
Properties of 17BETA-ESTRADIOL, CYCLODEXTRIN-ENCAPSULATED
| solubility | H2O: 25 mg/mL, may be clear to slightly hazy |
Safety information for 17BETA-ESTRADIOL, CYCLODEXTRIN-ENCAPSULATED
| Signal word | Danger |
| Pictogram(s) |
 Health Hazard GHS08  Environment GHS09 |
| GHS Hazard Statements |
H351:Carcinogenicity H362:Reproductive toxicity, effects on or via lactation H411:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P263:Avoid contact during pregnancy/while nursing. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P273:Avoid release to the environment. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for 17BETA-ESTRADIOL, CYCLODEXTRIN-ENCAPSULATED
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