1,4-dibromonaphthalene
- CAS NO.：83-53-4
- Empirical Formula: C10H6Br2
- Molecular Weight: 285.96
- MDL number: MFCD00041823
- EINECS: 201-484-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-26 21:18:56
What is 1,4-dibromonaphthalene?
Chemical properties
light orange-beige fine crystalline powder
The Uses of 1,4-dibromonaphthalene
1,4-Dibromonaphthalene is used in the annelation of PAHs. Also used in the synthesis of novel, orally active dual NK1/NK2 antagonists.
What are the applications of Application
1,4-Dibromonaphthalene is an inhibitor of NK-1R and NK-2R
What are the applications of Application
1,4-Dibromonaphthalene is mainly used for pharmaceutical intermediates. synthesis of tribromo methoxynaphthalenes from 1,4-dibromonaphthalene. starting material 1,4-dibromonaphthalene was prepared starting from naphthalene or 1-bromonaphthalene.
5,8-Dibromo-1,4-naphthoquinone and 5,8-diiodo-1,4-naphthoquinone were prepared from 1,4-dibromonaphthalene and 1,4-diiodonaphthalene.
Preparation
An environment-friendly method was developed to synthesize 1,4-dibromonaphthalene (1,4-DBN) using 1,3-dialkylimidazolium and pyridinium ionic liquids as catalysts, over which the yields of 1,4-DBN were obtained as high as 100%.
An environment-friendly method for synthesis of 1,4-dibromo-naphthalene in aqueous solution of ionic liquids
Properties of 1,4-dibromonaphthalene
| Melting point: | 80-82 °C |
| Boiling point: | 288.1°C (rough estimate) |
| Density | 1.8199 (estimate) |
| vapor pressure | 0-93.326Pa at 25℃ |
| refractive index | 1.6000 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform, DMSO (Slightly), Methanol (Slightly) |
| form | Crystalline Powder or Crystals |
| color | White to light beige |
| Water Solubility | 347.9ug/L(25 ºC) |
| CAS DataBase Reference | 83-53-4(CAS DataBase Reference) |
| EPA Substance Registry System | Naphthalene, 1,4-dibromo- (83-53-4) |
Safety information for 1,4-dibromonaphthalene
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 1,4-dibromonaphthalene
| InChIKey | IBGUDZMIAZLJNY-UHFFFAOYSA-N |
New Products
Tubulysin H (2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Diethyl Aluminium Cyanide (1.0 M in Toluene) CYCLOBUTYLAMINE HYDROCHLORIDE 3-Aminocyclobutanone hydrochloride Isoxazole, 3-[[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl]thio]-4,5-dihydro-5,5-dimethyl- 4,4-DIFLUOROPIPERIDINE 4-(Benzyloxy)-3-bromophenylacetic Acid 1-(1,1-Difluoroethyl)-2-fluorobenzene 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Fuel shell Imeglimin Hydrochloride IH 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol (1S,4S)-4- (3,4-dichlorophenyl) -N-methyl-1,2,3,4- tetrahydrona phthalen -1-amine .D-Mandelate (2,3-Dihydro- benzofuran-5-yl)- ethanol Lubiprostone Latanoprostene Bunod Magnesium Trisilicate Flame Retardant Zinc Borate 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carbonitrileRelated products of tetrahydrofuran
You may like
-
1,4-Dibromonaphthalene CAS 83-53-4View Details
83-53-4 -
Fuel shell 98%View Details
-
4,6-dichloro-2-propylthiopyrimidine-5-amine 145783-15-9 98%View Details
145783-15-9 -
Hydrogen Gas 98%View Details
-
590-17-0 Bromoacetonitrile 98%View Details
590-17-0 -
151767-02-1 Montelukast Sodium IP/USP 98%View Details
151767-02-1 -
Valacyclovir Hydrochloride IH 98%View Details
124832-27-5 -
2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 98%View Details
142569-70-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.