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HomeProduct name list1,4-DIAMINOBUTANE

1,4-DIAMINOBUTANE

Synonym(s):1,4-Butanediamine;1,4-Diaminobutane;Putrescine;Tetramethylenediamine

  • CAS NO.:110-60-1
  • Empirical Formula: C4H12N2
  • Molecular Weight: 88.15
  • MDL number: MFCD00008235
  • EINECS: 203-782-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:15:30
1,4-DIAMINOBUTANE Structural

What is 1,4-DIAMINOBUTANE?

Description

Putrescine (butane-1,4-diamine) and cadaverine (pentane-1,5-diamine) are foul-smelling compounds produced when amino acids decompose in decaying animals. They are also found in small amounts in living cells. Putrescine is formed by the decarboxylation of ornithine and arginine; cadaverine by the decarboxylation of lysine. L. Briege and O. Bocklisch isolated both compounds in 1885 and A. Ladenburg prepared them soon afterward.

Chemical properties

colourless liquid

The Uses of 1,4-DIAMINOBUTANE

1,4-Diaminobutane is used as a precursor in many biological systems and synthon for amido-ureas. It is involved in the synthesis of nylon 46 by reacting with adipic acid.

The Uses of 1,4-DIAMINOBUTANE

A GABA precursor in many biological systems.

The Uses of 1,4-DIAMINOBUTANE

GABA precursor in many biological systems and synthon for amido-ureas.

What are the applications of Application

1,4-Diaminobutane is a GABA precursor in many biological systems

Definition

ChEBI: A four-carbon alkane-alpha,omega-diamine. It is obtained by the breakdown of amino acids and is responsible for the foul odour of putrefying flesh.

Safety Profile

Poison by subcutaneous, intravenous, and rectal routes. Moderately toxic by ingestion. An experimental teratogen. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also 1,3-BUTANEDIAMINE and AMINES.

Properties of 1,4-DIAMINOBUTANE

Melting point: 27 °C
Boiling point: 158-160 °C(lit.)
Density  0.877 g/mL at 25 °C(lit.)
vapor pressure  436 Pa (25 °C)
refractive index  n20/D 1.457(lit.)
Flash point: 125 °F
storage temp.  Store below +30°C.
solubility  cell culture medium: 0.16 mg/mL
form  lyophilized powder
pka 10.8(at 20℃)
Specific Gravity 0.877
color  Clear colorless to slightly yellow
Odor animal rotting fish
explosive limit 0.7-11.2%(V)
Water Solubility  almost transparency
Sensitive  Air Sensitive & Hygroscopic
Merck  14,7947
BRN  605282
Stability: Stable. Incompatible with acids, acid chlorides, acid anhydrides, strong oxidizing agents. Flammable.
CAS DataBase Reference 110-60-1(CAS DataBase Reference)
EPA Substance Registry System 1,4-Butanediamine (110-60-1)

Safety information for 1,4-DIAMINOBUTANE

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H290:Corrosive to Metals
H302:Acute toxicity,oral
H311:Acute toxicity,dermal
H314:Skin corrosion/irritation
H330:Acute toxicity,inhalation
Precautionary Statement Codes P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 1,4-DIAMINOBUTANE

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