1,2-PHENYLENE PHOSPHOROCHLORIDATE

Synonym(s):o-Phenylene chlorophosphate;2-Chloro-1,3,2-benzodioxaphosphole 2-oxide;Catechol cyclophosphorochloridate

CAS NO.：1499-17-8
Empirical Formula: C6H4ClO3P
Molecular Weight: 190.52
MDL number: MFCD00005854
EINECS: 216-106-7
SAFETY DATA SHEET (SDS)
Update Date: 2022-12-21 16:56:50

1,2-PHENYLENE PHOSPHOROCHLORIDATE Structural

What is 1,2-PHENYLENE PHOSPHOROCHLORIDATE?

The Uses of 1,2-PHENYLENE PHOSPHOROCHLORIDATE

Reactant for preparation of:

Uridine diphosphate-glucose derivatives as potential chain terminators of β-glucan biosynthesis with antifungal activity
Vinyloxy phosphorus monomers

Phosphorylation agent

What are the applications of Application

o-Phenylene phosphorochloridate is a phosphorylation agent

Purification Methods

After distilling it in a vacuum, it sets to a colourless solid. It is soluble in pet ether, *benzene and slightly soluble in Et2O. [Khwaja et al. J Chem Soc (C) 2092 1970, Anschütz & Broeker Justus Liebigs Ann Chem 454 109 1927, Beilstein 6 IV 5602.]

Properties of 1,2-PHENYLENE PHOSPHOROCHLORIDATE

Melting point:	56-62 °C
Boiling point:	120 °C9 mm Hg(lit.)
Density	1.57±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Store in freezer, under -20°C
BRN	142368
EPA Substance Registry System	1,3,2-Benzodioxaphosphole, 2-chloro-, 2-oxide (1499-17-8)

Safety information for 1,2-PHENYLENE PHOSPHOROCHLORIDATE

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.