1,2-NAPHTHOQUINONE-4-SULFONIC ACID SODIUM SALT

Synonym(s):1,2-Naphthoquinone-4-sulfonic acid sodium salt;3,4-Dihydro-3,4-dioxo-1-naphthalenesulfonic acid sodium salt;Folin’s reagent;Sodium 1,2-naphthoquinone-4-sulfonate

CAS NO.：521-24-4
Empirical Formula: C10H5NaO5S
Molecular Weight: 260.2
MDL number: MFCD00001700
EINECS: 208-308-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-06-04 15:29:52

1,2-NAPHTHOQUINONE-4-SULFONIC ACID SODIUM SALT Structural

What is 1,2-NAPHTHOQUINONE-4-SULFONIC ACID SODIUM SALT?

Chemical properties

powder

The Uses of 1,2-NAPHTHOQUINONE-4-SULFONIC ACID SODIUM SALT

1,2-Naphthoquinone-4-sulfonic acid sodium salt is used in the characterization of phanerochaete chrysosporium. Used in the synthesis of carbohydrate based napthoquinones as anticancer agents.

The Uses of 1,2-NAPHTHOQUINONE-4-SULFONIC ACID SODIUM SALT

Colorimetric determination of amino acids and amines.

The Uses of 1,2-NAPHTHOQUINONE-4-SULFONIC ACID SODIUM SALT

Colorimetric determination of amino acids and amines1,2-Naphthoquinone-4-sulfonic acid sodium salt is used for the colorimetric determination of amino acids, amines and procaine hydrochloride in pharmaceutical preparations. It is also used in the characterization of phanerochaete chrysosporium. Further, it acts as an intermediate in the synthesis of carbohydrate based napthoquinones, which acts as anticancer agents.

Purification Methods

It forms yellow crystals from aqueous EtOH and should be dried at 80o in vacuo. Its solubility in H2O is 5% [Martin & Fieser Org Synth Coll Vol III 633 1955, Danielson J Biol Chem 101 507 1933, UV: Rosenblatt et al. Anal Chem 27 1290 1955]. [Beilstein 11 IV 668.]

Properties of 1,2-NAPHTHOQUINONE-4-SULFONIC ACID SODIUM SALT

Melting point:	289 °C (dec.)(lit.)
storage temp.	2-8°C
solubility	H₂O: 50 mg/mL, clear
form	solid
color	dark orange
Odor	Odorless
Water Solubility	Soluble in water and acetone. Slightly soluble in alcohol and ethanol. Insoluble in chloroform.
Merck	14,8646
BRN	4169788
Stability:	Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	521-24-4(CAS DataBase Reference)
EPA Substance Registry System	1,2-Naphthoquinone-4-sulfonic acid sodium salt (521-24-4)

Safety information for 1,2-NAPHTHOQUINONE-4-SULFONIC ACID SODIUM SALT

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.