1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Synonym(s):PC(6:0/6:0);(7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexyl)oxy]-3,5,9-trioxa-4-phosphapentadecan-1-aminium 4-oxide, inner salt;L -α-Dihexanoyllecithin;L -α-Phosphatidylcholine, dicaproyl;Dicaproyl-L -α-lecithin
- CAS NO.：34506-67-7
- Empirical Formula: C20H40NO8P
- Molecular Weight: 453.51
- MDL number: MFCD00050431
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:42
What is 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE?
Description
1,2-Dihexanoyl-sn-glycero-3-PC (DHPC-C6) is a synthetic phospholipid containing the short-chain (6:0) caproic acid inserted at the sn-1 and sn-2 positions. It is a substrate for phospholipase C isolated from B. cereus as well as phospholipase A2 isolated from A. halys blomhoffi and N. naja atra snake venom. DHPC is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.
The Uses of 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
L-α-Dihexanoyllecithin is used in the targeted delivery of adamantylated peptidoglycan immunomodulators in lipid nanocarriers.
Definition
ChEBI: 1,2-dihexanoyl-sn-glycero-3-phosphocholine is a phosphatidylcholine 12:0 in which both acyl groups are specified as hexanoyl. It has a role as a surfactant. It is functionally related to a hexanoic acid.
Properties of 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
| storage temp. | −20°C |
| solubility | DMF: > 20 mg/ml; DMSO: > 7 mg/ml; Ethanol: > 30 mg/ml; PBS (pH 7.2): > 250 μg/ml |
| form | solution |
| color | White to off-white |
Safety information for 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H336:Specific target organ toxicity,single exposure; Narcotic effects H351:Carcinogenicity H372:Specific target organ toxicity, repeated exposure H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
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