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HomeProduct name list1,2-Bis(chloromethyl)benzene

1,2-Bis(chloromethyl)benzene

Synonym(s):o-Xylylene dichloride;1,2-Bis(chloromethyl)benzene

  • CAS NO.:612-12-4
  • Empirical Formula: C8H8Cl2
  • Molecular Weight: 175.06
  • MDL number: MFCD00000903
  • EINECS: 210-291-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-12-26 17:07:23
1,2-Bis(chloromethyl)benzene Structural

What is 1,2-Bis(chloromethyl)benzene?

Chemical properties

white to light yellow crystal powde

The Uses of 1,2-Bis(chloromethyl)benzene

1,2-Bis(chloromethyl)benzene is used in solid-phase synthesis of large combinatorial variations of fundamental peptide unit 1 .

The Uses of 1,2-Bis(chloromethyl)benzene

α,α′?Dichloro-o-xylene was used in solid-phase synthesis of large combinatorial variations of fundamental peptide unit.

General Description

α,α′-Dichloro-o-xylene reacts with elemental tellurium and NaI in 2-methoxyethanol to form 1,1-diiodo-3,4-benzo-1-telluracyclopentane.

Safety Profile

Poison by intravenous route. Mutation data reported. See also CHLORINATED HYDROCARBONS, AROMATIC. When heated to decomposition it emits toxic Cl-.

Properties of 1,2-Bis(chloromethyl)benzene

Melting point: 51-55 °C (lit.)
Boiling point: 239-241 °C (lit.)
Density  1.3930
refractive index  1.5544 (estimate)
Flash point: 226 °F
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  soluble in Methanol
form  Crystals or Crystalline Powder
color  white to light beige
Water Solubility  hydrolysis
BRN  2043675
CAS DataBase Reference 612-12-4(CAS DataBase Reference)
NIST Chemistry Reference Benzene, 1,2-bis(chloromethyl)-(612-12-4)
EPA Substance Registry System 1,2-Bis(chloromethyl)benzene (612-12-4)

Safety information for 1,2-Bis(chloromethyl)benzene

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Environment
GHS09
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P273:Avoid release to the environment.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 1,2-Bis(chloromethyl)benzene

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