11-MERCAPTOUNDECANOIC ACID
Synonym(s):MUA;MUDA
- CAS NO.:71310-21-9
- Empirical Formula: C11H22O2S
- Molecular Weight: 218.36
- MDL number: MFCD00022096
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-19 22:39:07
What is 11-MERCAPTOUNDECANOIC ACID?
Chemical properties
White to light yellow solid
The Uses of 11-MERCAPTOUNDECANOIC ACID
MUA is used for the carboxylic acid functionalization of 1-dodecanethiol-protected gold nanoparticles (AuNPs) by Murray place-displacement reaction generally utilized in biomedical applications. It can also be used to modify the surface of platinum nanoparticles (PtNPs) by creating a ligand nano-assembly with a high surface coverage for use in surface-enhanced Raman spectroscopy (SERS). A single cell biochip platform can be developed utilizing a cell attachment technique with MUA forming a SAM that was attached to single cells. MUA may be used to prepare a tetrafluorophenyl-activated ester self-assembled monolayer to immobilize amine-modified oligonucleotides and DNA. It is also used to create 3D-assembled gold nanostructures for plasmonic biosensors.
The Uses of 11-MERCAPTOUNDECANOIC ACID
MUA as a self-assembled monolayer (SAM) is used as a microfluidic integrated surface plasmon resonance (SPR) for detection and quantification of bacteria in medical diagnostics. It is also used to bio-functionalize the screen printed gold electrodes (SPGEs) that are used for the detection and quantification of dengue. It also forms monolayers on gold nanoparticles (AuNPs) attached via thiol groups. MUA incorporated AuNPs exhibit excellent fluorescence properties which may be used for metal ion detection in serum samples.
What are the applications of Application
11-Mercaptoundecanoic acid is an alkyl acid thiol compound used for SAMs
General Description
11-mercaptoundecanoic acid (MUA) has long alkane chains and carboxyl containing thiols that are highly packed and form a self-assembled monolayer (SAM). It modifies the surface of nanoparticles to facilitate their dispersion into water and solvent based mediums.
Properties of 11-MERCAPTOUNDECANOIC ACID
Melting point: | 46-50 °C (lit.) |
Boiling point: | 159 °C(Press: 1 Torr) |
Density | 0.998±0.06 g/cm3(Predicted) |
Flash point: | 110 °C |
storage temp. | 2-8°C |
solubility | Chloroform (Sparingly), Methanol (Slightly) |
pka | 4.78±0.10(Predicted) |
form | Solid |
color | White to Off-White |
Safety information for 11-MERCAPTOUNDECANOIC ACID
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 11-MERCAPTOUNDECANOIC ACID
InChIKey | GWOLZNVIRIHJHB-UHFFFAOYSA-N |
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