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Home Product name list11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2

11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2

CAS NO.：53658-98-3
Empirical Formula: C22H36O4
Molecular Weight: 364.52
MDL number: MFCD00135216
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 09:03:09

11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2 Structural

What is 11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2?

Description

11-deoxy-16,16-dimethyl PGE₂ is a stable synthetic analog of PGE₂. It is an agonist for both EP₂ and EP₃ receptors. It is an effective inhibitor of gastric acid secretion and ulcer formation in the rat, with ED₅₀ values of 1 mg/kg and 0.021 mg/kg respectively. It is 900 times more potent than PGF_2α in the contraction of human respiratory tract smooth muscle in vitro.

The Uses of 11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2

AY 24609 is an analogue of PGE2 and a selective EP2 and EP3 receptors agonist. It also inhibits gastric acid secretion and ulcer formation in rat.

What are the applications of Application

11-deoxy-16,16-dimethyl Prostaglandin E2 is an analog of PGE2 shown to act as a selective agonist for EP2 & EP3 receptors

Definition

ChEBI: 11-Deoxy-16,16-dimethyl-PGE2 is a prostanoid.

Properties of 11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2

solubility

DMF: >100 mg/ml (from PGE2); DMSO: >100 mg/ml (from PGE2); Ethanol: >100 mg/ml (from PGE2); PBS pH 7.2: >5 mg/ml (from PGE2)

Safety information for 11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2

Computed Descriptors for 11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2

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TRIMOPROSTIL

11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2

11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2

16,16-DIMETHYL PGE2 4-(4-ACETAMIDOBENZAMIDO) PHENYL ESTER

16,16-DIMETHYL PGE2 4-(4-ACETAMIDOBENZAMIDO) PHENYL ESTER

11-DEOXY PROSTAGLANDIN E2

11-DEOXY PROSTAGLANDIN E2

16,16-DIMETHYL PROSTAGLANDIN E2

16,16-DIMETHYL PROSTAGLANDIN E2

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