1,1'-Bis(diphenylphosphino)ferrocene-palladium(II)dichloride dichloromethane complex

CAS NO.：95464-05-4
Empirical Formula: C34H28Cl2FeP2Pd.CH2Cl2
Molecular Weight: 816.63
MDL number: MFCD00792899
EINECS: 619-128-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-11 15:28:25

What is 1,1'-Bis(diphenylphosphino)ferrocene-palladium(II)dichloride dichloromethane complex?

Chemical properties

orange/red solid

The Uses of 1,1'-Bis(diphenylphosphino)ferrocene-palladium(II)dichloride dichloromethane complex

suzuki reaction

The Uses of 1,1'-Bis(diphenylphosphino)ferrocene-palladium(II)dichloride dichloromethane complex

1,1'-Bis(diphenylphosphino)ferrocene-palladium(II)dichloride dichloromethane complex is used in the preparation of imidazoles, benzimidazoles, and tetrahydropyrimidines,it is also used as a catalyst for Suzuki and Stile couplings.

What are the applications of Application

[1,1′-Bis(diphenylphosphino)ferrocene]palladium(II) Dichloride Dichloromethane Adduct is a precurosor used in the preparation of imidazoles, benzimidazoles, and tetrahydropyrimidines

What are the applications of Application

1,1'-Bis(diphenylphosphino)ferrocene-palladium(II)dichloride dichloromethane complex is an organometallic compound that can be used as a noble metal catalyst for carbonylation reactions, cross-coupling reactions, Suzuki reaction.

Synthesis

1. Dissolve 2.00 grams of sodium palladium chloride in 30mL of anhydrous ethanol to obtain the ethanol solution of sodium palladium chloride;
2. Dissolve 4.15 grams of 1,1 '-bis (diphenylphosphine) ferrocene in 41mL dichloromethane to obtain 1,1' -bis (diphenylphosphine) ferrocene dichloromethane solution;
3. Under stirring conditions, add the ethanol solution of sodium palladite chloride in step 1 to dichloromethane solution of 1, 1 '-bis (diphenylphosphine) ferrocene in step 2. Stir and react for 1h at 25℃. 1,1'-Bis(diphenylphosphino)ferrocene-palladium(II)dichloride dichloromethane complex crystal, yield 90.46%.
In this method, the target product 1,1'-Bis(diphenylphosphino)ferrocene-palladium(II)dichloride dichloromethane complex was synthesized directly with dichloromethane as the solvent in one step, eliminating the synthesis process of precursor PDCl2 (DPPF). The reaction process is simple, the synthesis cycle is short, easy to operate, and the purity of the synthesized product is 99.4%.

Properties of 1,1'-Bis(diphenylphosphino)ferrocene-palladium(II)dichloride dichloromethane complex

Melting point:	275-280 °C(lit.)
Density	1 g/cm³
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Powder
color	orange-red
Water Solubility	Insoluble in water.
Stability:	Light Sensitive
CAS DataBase Reference	95464-05-4(CAS DataBase Reference)

Safety information for 1,1'-Bis(diphenylphosphino)ferrocene-palladium(II)dichloride dichloromethane complex

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.