1-Oleoyl lysophosphatidic acid sodium salt
Synonym(s):1-Oleoyl-sn-glycerol 3-phosphate sodium salt;3-sn-Lysophosphatidic acid, 1-oleoyl sodium salt;LPA sodium salt
- CAS NO.:22556-62-3
- Empirical Formula: C21H42NaO7P
- Molecular Weight: 460.52
- MDL number: MFCD00142682
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is 1-Oleoyl lysophosphatidic acid sodium salt?
The Uses of 1-Oleoyl lysophosphatidic acid sodium salt
Oleoyl-L-α-lysophosphatidic Acid reduces the organ injury caused by endotoxemia in the rat.?It may be useful in the treatment of shock of various etiologies.
General Description
Lysophosphatidic acid (LPA) is an essential metabolite for membrane biosynthesis. LPA interacts with the G protein-coupled receptors (GPCRs), called the LPA receptor and mediates signaling. Oleoyl-L-α-lysophosphatidic acid activates the receptor LPA4. In keratinocytes, oleoyl-L-α-lysophosphatidic acid promotes growth to some extent.
Biochem/physiol Actions
Endogenous agonist for LPA1 and LPA2 receptors. LPA does not induce angiogenesis, but has effects on endothelial cell physiology that are similar to those of sphingosine 1-phosphate. Induces cell migration of cancer and non-cancer cells.
Properties of 1-Oleoyl lysophosphatidic acid sodium salt
storage temp. | -20°C |
form | solid |
color | white |
Water Solubility | Soluble in water up to 5mg/ml with sonication |
Sensitive | Light & Air Sensitive & Hygroscopic |
Safety information for 1-Oleoyl lysophosphatidic acid sodium salt
Computed Descriptors for 1-Oleoyl lysophosphatidic acid sodium salt
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