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HomeProduct name list1-Oleoyl lysophosphatidic acid sodium salt

1-Oleoyl lysophosphatidic acid sodium salt

Synonym(s):1-Oleoyl-sn-glycerol 3-phosphate sodium salt;3-sn-Lysophosphatidic acid, 1-oleoyl sodium salt;LPA sodium salt

1-Oleoyl lysophosphatidic acid sodium salt Structural

What is 1-Oleoyl lysophosphatidic acid sodium salt?

The Uses of 1-Oleoyl lysophosphatidic acid sodium salt

Oleoyl-L-α-lysophosphatidic Acid reduces the organ injury caused by endotoxemia in the rat.?It may be useful in the treatment of shock of various etiologies.

General Description

Lysophosphatidic acid (LPA) is an essential metabolite for membrane biosynthesis. LPA interacts with the G protein-coupled receptors (GPCRs), called the LPA receptor and mediates signaling. Oleoyl-L-α-lysophosphatidic acid activates the receptor LPA4. In keratinocytes, oleoyl-L-α-lysophosphatidic acid promotes growth to some extent.

Biochem/physiol Actions

Endogenous agonist for LPA1 and LPA2 receptors. LPA does not induce angiogenesis, but has effects on endothelial cell physiology that are similar to those of sphingosine 1-phosphate. Induces cell migration of cancer and non-cancer cells.

Properties of 1-Oleoyl lysophosphatidic acid sodium salt

storage temp.  -20°C
form  solid
color  white
Water Solubility  Soluble in water up to 5mg/ml with sonication
Sensitive  Light & Air Sensitive & Hygroscopic

Safety information for 1-Oleoyl lysophosphatidic acid sodium salt

Computed Descriptors for 1-Oleoyl lysophosphatidic acid sodium salt

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