1-O-HEXADECYL-SN-GLYCEROL
Synonym(s):1-O-hexadecyl-sn-glycerol (HG)
- CAS NO.：506-03-6
- Empirical Formula: C19H40O3
- Molecular Weight: 316.52
- MDL number: MFCD00151171
- EINECS: 208-026-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-12-21 14:55:28
What is 1-O-HEXADECYL-SN-GLYCEROL?
Description
1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether. It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 (PGE2; ) in normal human epidermal keratinocytes (NHEKs). 1-O-Hexadecyl-sn-glycerol (50 μM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury.
The Uses of 1-O-HEXADECYL-SN-GLYCEROL
1-O-Hexadecyl-sn-glycerol restores plasmalogen levels in Chinese hamster ovary (CHO) cells and human pulmonary arterial endothelial cells (PAEC). Plasmalogen may play a role in protecting animal cells against photosensitized killing.
What are the applications of Application
1-O-Hexadecyl-sn-glycerol is a naturally occuring ether lipid
Definition
ChEBI: A 1-n-hexadecyl analogue of an optically active alkylglycerol compound.
Purification Methods
Recrystallise it from hexane. [Beilstein 1 III 2322.]
Properties of 1-O-HEXADECYL-SN-GLYCEROL
| Melting point: | 64° |
| Boiling point: | bp0.005 120° |
| alpha | D20 +3.0° (c = 1.16 in chloroform) |
| Density | 1.0054 (rough estimate) |
| refractive index | 1.4410 (estimate) |
| storage temp. | -15°C |
| solubility | DMF: 16 mg/ml; DMSO: 0.16 mg/ml; Ethanol: 5 mg/ml |
| form | A crystalline solid |
| pka | 13.68±0.20(Predicted) |
Safety information for 1-O-HEXADECYL-SN-GLYCEROL
Computed Descriptors for 1-O-HEXADECYL-SN-GLYCEROL
New Products
Tubulysin C Tubulysin F (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin G Tubulysin A 2,2-Difluoropropylamine hydrochloride tetrahydro-4-methyl-2H-pyran 1-(1,1-Difluoroethyl)-2-fluorobenzene 2H-Pyran, 4-ethynyltetrahydro- 3-FLUOROPYRROLIDINE HYDROCHLORIDE 4-CYANO-TETRAHYDROPYRAN-4-CARBOXYLIC ACID Fuel shell Imeglimin Hydrochloride IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Calcium Sodium Phosphosilicate IH 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Lubiprostone Magnesium Trisilicate Latanoprostene Bunod Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate 1H-Imidazole-4-carbonitrileRelated products of tetrahydrofuran
![1,2-DIOCTADECANOYL-SN-GLYCERO-3-PHOSPHO-RAC-[1-GLYCEROL] AMMONIUM SALT](https://img.chemicalbook.in/CAS/GIF/108347-80-4.gif)
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