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HomeProduct name list1-Naphthyl acetate

1-Naphthyl acetate

Synonym(s):α-Naphthyl acetate

  • CAS NO.:830-81-9
  • Empirical Formula: C12H10O2
  • Molecular Weight: 186.21
  • MDL number: MFCD00003922
  • EINECS: 212-599-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-20 11:41:24
1-Naphthyl acetate Structural

What is 1-Naphthyl acetate?

Chemical properties

1-Naphthyl acetate is white to light yellowish or slightly pink

The Uses of 1-Naphthyl acetate

1-Naphthyl acetate is usually used in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors.

The Uses of 1-Naphthyl acetate

1-Naphthyl Acetate is used in preparation method for synthesizing Ph Acetate derivative by Acetylation of Phenol compound.

The Uses of 1-Naphthyl acetate

1-Naphthyl acetate may be used in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors. It may be employed as substrate to investigate the distribution of non-specific carboxylic esterases (EC 3.1.1) in the digestive tract of perch, Perm fliiviatilis L.

What are the applications of Application

1-Naphthyl acetate is a useful staining tool for identification of macrophages

Synthesis Reference(s)

Synthetic Communications, 21, p. 989, 1991 DOI: 10.1080/00397919108019787
Tetrahedron Letters, 30, p. 95, 1989 DOI: 10.1016/S0040-4039(01)80332-4

General Description

1-Naphthyl acetate is a 1-napthyl ester. Mechanism of photo-Fries rearrangement of 1-naphthyl acetate has been studied using steady state photolysis and laser flash photolysis. Kinetics of photo-Fries rearrangement of 1-napthyl acetate has been studied using steady-state, time-resolved chemically induced dynamic nuclear polarization (CIDNP) and flash photolysis methods.

Purification Methods

Chromatograph the acetate on silica gel and crystallise as the 2-isomer below. The 2,4,7-trinitrofluoren-9-one complex has m 120o (from EtOH). [Beilstein 6 H 608, 6 III 2928, 6 IV 4217.]

Properties of 1-Naphthyl acetate

Melting point: 43-46 °C (lit.)
Boiling point: 118 °C / 1mmHg
Density  1.1032 (rough estimate)
refractive index  1.6010 (estimate)
Flash point: 113 °C
storage temp.  -20°C
solubility  dioxane: 0.1 g/mL, clear, colorless
form  Crystalline Powder or Crystals
color  White to light yellow or slightly pink
Odor Odorless
Sensitive  Moisture Sensitive
BRN  2046403
CAS DataBase Reference 830-81-9(CAS DataBase Reference)
NIST Chemistry Reference 1-Naphthyl acetate(830-81-9)
EPA Substance Registry System 1-Naphthyl acetate (830-81-9)

Safety information for 1-Naphthyl acetate

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H318:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 1-Naphthyl acetate

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