1-Methylcyclopentanol

CAS NO.：1462-03-9
Empirical Formula: C6H12O
Molecular Weight: 100.16
MDL number: MFCD00001364
EINECS: 215-963-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-31 13:32:20

What is 1-Methylcyclopentanol?

Chemical properties

white crystalline low melting solid

The Uses of 1-Methylcyclopentanol

1-Methylcyclopentanol is used as a reagent in the synthesis of cis-2,5-dicyanopyrrolidine inhibitors of dipeptidyl peptidase IV. It is also used in the preparation of Lomifylline (L470200) which is a methylxanthine analog that induces Ca2+-release from intracellular stores via the ryanodine receptor.

Synthesis Reference(s)

Tetrahedron Letters, 29, p. 6753, 1988 DOI: 10.1016/S0040-4039(00)82446-6

Properties of 1-Methylcyclopentanol

Melting point:	36-37 °C (lit.)
Boiling point:	135-136 °C (lit.)
Density	0.904 g/mL at 25 °C (lit.)
refractive index	1.4429
Flash point:	105 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform, Methanol (Slightly)
pka	15.38±0.20(Predicted)
form	powder to lump
color	White to Almost white
Dielectric constant	6.9699999999999998
CAS DataBase Reference	1462-03-9(CAS DataBase Reference)
NIST Chemistry Reference	Cyclopentanol, 1-methyl-(1462-03-9)

Safety information for 1-Methylcyclopentanol

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H228:Flammable solids H302:Acute toxicity,oral H318:Serious eye damage/eye irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.