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HomeProduct name list1-METHYL-3-INDOLEACETIC ACID

1-METHYL-3-INDOLEACETIC ACID

Synonym(s):2-(N-Methylindole-3-yl)acetic acid;NSC 78007

1-METHYL-3-INDOLEACETIC ACID Structural

What is 1-METHYL-3-INDOLEACETIC ACID?

Chemical properties

Light Brown Solid

The Uses of 1-METHYL-3-INDOLEACETIC ACID

1-Methylindole-3-acetic Acid is a N-methylated derivative of Indole-3-acetic acid, a natural auxin, with plant growth regulating activity.

The Uses of 1-METHYL-3-INDOLEACETIC ACID

  • Reactant for enantioselective preparation of α-aryl alkylcarboxylic acids
  • Reactant for preparation of PKC inhibitor methylindolylpyridinylmethylpiperidinylindolylpyrroledione for protein kinase C imaging
  • Reactant for stereoselective preparation of δ-lactones via Michael addition/lactonization with unsaturated carboxylates
  • Reactant for stereoselective preparation of vindorosine, vindoline, and analogs
  • Reactant for preparation of (indolyl)pyrrol-2-ones as VEGF-R inhibitors, antiangiogenic agents, and protein kinase inhibitors
  • Reactant for synthesis of 3-aryl-5-alkyl-2,5-dihydrofuran-2-ones and their carbanalogues as antifungal agents

What are the applications of Application

1-Methyl-3-indoleacetic acid is an important precursor to PKC inhibitor methylindolypyridinylmet

General Description

1-Methyl-3-indoleacetic acid is an indole derivative. Direct and riboflavin- or Rose-Bengal-sensitized photo-oxidation of 1-methyl-3-indoleacetic acid in aqueous buffer (pH 5 or pH 8) containing 10% methanol has been studied.

Properties of 1-METHYL-3-INDOLEACETIC ACID

Melting point: 126-128 °C (lit.)
Boiling point: 392.0±17.0 °C(Predicted)
Density  1.20±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  Chloroform, Methanol
pka 4.53±0.30(Predicted)
form  Crystalline Powder
color  White to tan

Safety information for 1-METHYL-3-INDOLEACETIC ACID

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H318:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 1-METHYL-3-INDOLEACETIC ACID

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