1-Methyl-2-imidazolecarboxaldehyde

CAS NO.：13750-81-7
Empirical Formula: C5H6N2O
Molecular Weight: 110.11
MDL number: MFCD01321308
EINECS: 627-478-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-06-13 17:03:25

What is 1-Methyl-2-imidazolecarboxaldehyde?

Chemical properties

White to yellow crystalline mass,

The Uses of 1-Methyl-2-imidazolecarboxaldehyde

1-Methyl-2-imidazolecarboxaldehyde may be used in the synthesis of:

Schiff bases
ligand N,N-dimethyl-N′-(1-methylimidazole-2-ylmethyl)-ethylenediamine
[(bis(1-methylimidazol-2-yl)methyl)(2-(pyridyl-2-yl)ethyl)amine]

The Uses of 1-Methyl-2-imidazolecarboxaldehyde

It is an important raw material and intermediate used in organic synthesis, Pharmaceuticals, agrochemicals and dyestuffs.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 26, p. 121, 1983 DOI: 10.1021/jm00356a001

General Description

1-Methyl-2-imidazolecarboxaldehyde is a heterocyclic building block. It affords tripodal ligands on condensation reaction with tris-(2-aminoethyl)amine (tren). These tripodal ligands react with iron(III) salts in the presence of air to afford iron(II) complexes. Its vibrational spectral studies have been reported.

Properties of 1-Methyl-2-imidazolecarboxaldehyde

Melting point:	36-39 °C (lit.)
Boiling point:	70-74 °C/1 mmHg (lit.)
Density	1.2111 (rough estimate)
refractive index	1.5090 (estimate)
Flash point:	215 °F
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
pka	4.17±0.25(Predicted)
form	Liquid
color	Clear colorless to yellow
Water Solubility	Soluble in water.
Sensitive	Air Sensitive
CAS DataBase Reference	13750-81-7(CAS DataBase Reference)
NIST Chemistry Reference	1H-imidazole-2-carboxaldehyde, 1-methyl-(13750-81-7)

Safety information for 1-Methyl-2-imidazolecarboxaldehyde

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.