1-METHYL-1-CYCLOHEXANECARBOXYLIC ACID

CAS NO.：1123-25-7
Empirical Formula: C8H14O2
Molecular Weight: 142.2
MDL number: MFCD00001463
EINECS: 214-371-3
SAFETY DATA SHEET (SDS)
Update Date: 2024-07-14 20:44:35

What is 1-METHYL-1-CYCLOHEXANECARBOXYLIC ACID?

Chemical properties

WHITE TO YELLOW CRYSTALS OR CRYSTALLINE POWDER

The Uses of 1-METHYL-1-CYCLOHEXANECARBOXYLIC ACID

1-Methyl-1-cyclohexanecarboxylic acid was used as internal standard during the determination of valproic acid metabolites. Also been used as an anticonvulsant drug and causes maturation of murine neuroblastoma cells in vitro. Used in the synthesis of p38 map kinase.

What are the applications of Application

1-Methyl-1-cyclohexanecarboxylic acid is the structural analog of valproic acid used as an internal standard and anticonvulsant drug

Synthesis Reference(s)

The Journal of Organic Chemistry, 38, p. 3633, 1973 DOI: 10.1021/jo00960a047

General Description

1-Methyl-1-cyclohexanecarboxylic acid is the structural analog of valproic acid and its pharmacokinetic action has been studied in female Sprague-Dawley rats.

Biochem/physiol Actions

1-Methyl-1-cyclohexanecarboxylic acid is an anticonvulsant drug and causes maturation of murine neuroblastoma cells in vitro.

Properties of 1-METHYL-1-CYCLOHEXANECARBOXYLIC ACID

Melting point:	36-39 °C(lit.)
Boiling point:	234 °C(lit.)
Density	1.0037 (rough estimate)
refractive index	1.4600 (estimate)
Flash point:	213 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Soluble in chloroform and methanol.
form	Solid
pka	pK1:5.13 (25°C)
color	Brown Low Melting
BRN	1859220
CAS DataBase Reference	1123-25-7(CAS DataBase Reference)

Safety information for 1-METHYL-1-CYCLOHEXANECARBOXYLIC ACID

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.