1-Hydroxyethylethoxypiperazine

Synonym(s):2-[2-(1-Piperazinyl)ethoxy]ethanol

CAS NO.：13349-82-1
Empirical Formula: C8H18N2O2
Molecular Weight: 174.24
MDL number: MFCD00074931
EINECS: 1533716-785-6
SAFETY DATA SHEET (SDS)
Update Date: 2024-03-25 20:41:16

1-Hydroxyethylethoxypiperazine Structural

What is 1-Hydroxyethylethoxypiperazine?

Chemical properties

Yellow-Brown Oil

The Uses of 1-Hydroxyethylethoxypiperazine

1-Hydroxyethylethoxypiperazine is used as a Quetiapine intermediate.

The Uses of 1-Hydroxyethylethoxypiperazine

1-[2-(2-Hydroxyethoxy)ethyl]piperazine may be used in chemical synthesis.

Definition

ChEBI: 1-(2-(2-Hydroxyethoxy)ethyl)piperazine is a N-alkylpiperazine.

Health hazards

May cause eye and skin irritation. May cause respiratory and digestive tract irritation. The toxicological properties of this material have not been fully investigated.

Properties of 1-Hydroxyethylethoxypiperazine

Boiling point:	112-114 °C0.25 mm Hg(lit.)
Density	1.061 g/mL at 25 °C(lit.)
refractive index	n20/D 1.497(lit.)
Flash point:	>230 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly)
form	Liquid
pka	14.41±0.10(Predicted)
Specific Gravity	1.061
color	Clear colorless to yellow-brownish
InChI	InChI=1S/C8H18N2O2/c11-6-8-12-7-5-10-3-1-9-2-4-10/h9,11H,1-8H2
CAS DataBase Reference	13349-82-1(CAS DataBase Reference)
NIST Chemistry Reference	1-(2-(2-Hydroxyethoxy)ethyl)piperazine(13349-82-1)

Safety information for 1-Hydroxyethylethoxypiperazine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.