1-hydrazino-3-(methylthio)propan-2-ol
- CAS NO.:14359-97-8
- Empirical Formula: C4H12N2OS
- Molecular Weight: 136.22
- MDL number: MFCD13152171
- EINECS: 238-332-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-06-27 13:31:27
What is 1-hydrazino-3-(methylthio)propan-2-ol ?
Chemical properties
White powder
The Uses of 1-hydrazino-3-(methylthio)propan-2-ol
1-hydrazino-3-(methylthio)propan-2-ol, also known as 3-methylmercapto-2-hydroxy-propyl hydrazine, is an important organic reagent that can be used as a building block for the synthesis of many organic compounds. It can be used to synthesize N-amino-5-methylmercapto-methyl-2-oxazolidinone which is an intermediate of nifuratel.
Synthesis
Add 226.25g hydrazine hydrate to 1000ml reaction flask, heat to 90℃, and add 104.17g of glycidyl ether under stirring. The temperature of the reaction system was controlled at 90℃, and then the excess hydrazine hydrate was concentrated under reduced pressure to obtain 120.10g thick colorless liquid. The purity of the gas phase was 96.8%, namely 1-hydrazino-3-(methylthio)propan-2-ol, and the yield was 88.30%.
Properties of 1-hydrazino-3-(methylthio)propan-2-ol
Boiling point: | 128-130 °C(Press: 1 Torr) |
Density | 1.145±0.06 g/cm3(Predicted) |
pka | 13.98±0.20(Predicted) |
Safety information for 1-hydrazino-3-(methylthio)propan-2-ol
Computed Descriptors for 1-hydrazino-3-(methylthio)propan-2-ol
New Products
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