1-Hexyne

Synonym(s):1-Hexyne

CAS NO.：693-02-7
Empirical Formula: C6H10
Molecular Weight: 82.14
MDL number: MFCD00009504
EINECS: 211-736-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-12-18 14:08:57

What is 1-Hexyne?

Chemical properties

colourless liquid

The Uses of 1-Hexyne

1-Hexyne is used in the preparation of tricyclic isoindolinone scaffold by undergoing hydrozirconation and ring-closing metathesis. It is used to prepare trans-1,2-bis(5-thianthreniumyl)alkene tetrafluoroborate by reacting with thianthrene cation radical tetrafluoroborate.

Definition

ChEBI: 1-hexyne is a terminal acetylenic compound that is hexane carrying a triple bond at position 1. It is a terminal acetylenic compound, an alkyne and a volatile organic compound.

General Description

1-Hexyne reacted with thianthrene cation radical tetrafluoroborate to form trans-1,2-bis(5-thianthreniumyl)alkene tetrafluoroborate.

Hazard

Probably flammable.

Purification Methods

Distil it from NaBH4 to remove peroxides. Stand over sodium for 24hours, then fractionally distil it under reduced pressure. Also dry it by repeated vacuum transfer into freshly activated 4A molecular sieves, followed by vacuum transfer onto Na/K alloy and stirring for 1hour before fractionally distilling. [Beilstein 1 IV 1006.]

Properties of 1-Hexyne

Melting point:	-132 °C
Boiling point:	71-72 °C(lit.)
Density	0.715 g/mL at 25 °C(lit.)
vapor pressure	253 mm Hg ( 37.7 °C)
refractive index	n20/D 1.399(lit.)
Flash point:	−6 °F
storage temp.	Store at +2°C to +8°C.
solubility	0.36g/l (experimental)
form	Liquid
color	Clear colorless
Specific Gravity	0.715
Water Solubility	Miscible with organic solvents. Immiscible with water.
BRN	635687
Stability:	Stable. Incompatible with strong oxidizing agents. Highly flammable - readily forms explosive mixtures with air.
CAS DataBase Reference	693-02-7(CAS DataBase Reference)
NIST Chemistry Reference	1-Hexyne(693-02-7)
EPA Substance Registry System	1-Hexyne (693-02-7)

Safety information for 1-Hexyne

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H225:Flammable liquids H304:Aspiration hazard H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P331:Do NOT induce vomiting. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.