1-Cyano-1-cyclopropanecarboxylic acid

CAS NO.：6914-79-0
Empirical Formula: C5H5NO2
Molecular Weight: 111.1
MDL number: MFCD00190651
SAFETY DATA SHEET (SDS)
Update Date: 2022-11-11 11:01:00

What is 1-Cyano-1-cyclopropanecarboxylic acid?

Chemical properties

white to light brown crystalline powder

The Uses of 1-Cyano-1-cyclopropanecarboxylic acid

1-Cyano-1-cyclopropanecarboxylic acid may be used in the synthesis of amidine-based nanomolar sphingosine kinase1 subtype-selective inhibitors.

Synthesis Reference(s)

The Journal of Organic Chemistry, 40, p. 2969, 1975 DOI: 10.1021/jo00908a030

General Description

1-Cyano-1-cyclopropanecarboxylic acid (1-Cyanocyclopropanecarboxylic acid) is a substituted cyclopropane. It is the intermediate formed during homoconjugate addition of nucleophiles to cyclopropane-1,1-dicarboxylate derivative.

Properties of 1-Cyano-1-cyclopropanecarboxylic acid

Melting point:	140 °C (lit.)
Boiling point:	142 °C
Density	1.3113 (rough estimate)
refractive index	1.4260 (estimate)
storage temp.	2-8°C
pka	2.31±0.20(Predicted)
CAS DataBase Reference	6914-79-0(CAS DataBase Reference)

Safety information for 1-Cyano-1-cyclopropanecarboxylic acid

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.