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HomeProduct name list1-butylbiguanide

1-butylbiguanide

  • CAS NO.:692-13-7
  • Empirical Formula: C6H15N5
  • Molecular Weight: 157.2168
  • MDL number: MFCD00242653
  • EINECS: 2117264
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-28 16:48:35
1-butylbiguanide Structural

What is 1-butylbiguanide?

The Uses of 1-butylbiguanide

Buformin, clinically used for diabetes mellitus, is known to improve resistance to insulin in patients. It suppresses the expression of glyceraldehyde 3-phosphate dehydrogenase

Definition

ChEBI: Buformin is a member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect. It has a role as a hypoglycemic agent, a geroprotector, a radiosensitizing agent, an antineoplastic agent and an antiviral agent. It is functionally related to a biguanide.

brand name

Adebit;Andebit;Andelit;Andere;Biforon;Bigunal;Biquinal;Bs-5892;Bufonamin;Bulbonin;Diabrin;Dutformin;Gliporal;Insulamin;Krebon;Panformin;Silubin retard;Sindiatil;Tidemol retard;Ziavetine.

World Health Organization (WHO)

Buformin is an analogue of phenformin. See WHO comment for phenformin. (Reference: (WHODI) WHO Drug Information, 2, 4, 1977)

Properties of 1-butylbiguanide

Melting point: 174-176 °C
Boiling point: 271.89°C (rough estimate)
Density  1.0291 (rough estimate)
refractive index  1.8070 (estimate)
pka 12.27±0.10(Predicted)

Safety information for 1-butylbiguanide

Computed Descriptors for 1-butylbiguanide

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